Document Detail


Rates and cost of hospitalization before and after initiation of antiretroviral therapy in urban and rural settings in South Africa.
MedLine Citation:
PMID:  23187948     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Few studies have compared hospitalizations before and after antiretroviral therapy (ART) initiation in the same patients. We analyzed the cost of hospitalizations among 3906 adult patients in 2 South African hospitals, 30% of whom initiated ART. Hospitalizations were 50% and 40% more frequent and 1.5 and 2.6 times more costly at a CD4 cell count, 100 cells/mm(3) when compared with 200–350 cells/mm(3) in the pre-ART and ART period, respectively. Mean inpatient cost per patient year was USD 117 (95%confidence interval, 85 to 158) for patients on ART and USD 72(95% confidence interval, 56 to 89) for pre-ART patients. Raising ART eligibility thresholds could avoid the high cost of hospitalization before and immediately after ART initiation.
Authors:
Gesine Meyer-Rath; Alana T Brennan; Matthew P Fox; Tebogo Modisenyane; Nkeko Tshabangu; Lerato Mohapi; Sydney Rosen; Neil Martinson
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Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.    
Journal Detail:
Title:  Journal of acquired immune deficiency syndromes (1999)     Volume:  62     ISSN:  1944-7884     ISO Abbreviation:  J. Acquir. Immune Defic. Syndr.     Publication Date:  2013 Mar 
Date Detail:
Created Date:  2013-08-12     Completed Date:  2013-08-20     Revised Date:  2014-03-07    
Medline Journal Info:
Nlm Unique ID:  100892005     Medline TA:  J Acquir Immune Defic Syndr     Country:  United States    
Other Details:
Languages:  eng     Pagination:  322-328     Citation Subset:  IM; X    
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MeSH Terms
Descriptor/Qualifier:
Adult
Anti-Retroviral Agents / therapeutic use*
CD4 Lymphocyte Count
Female
HIV Infections / drug therapy*
Hospitalization / economics*,  statistics & numerical data*
Humans
Male
Rural Population / statistics & numerical data
South Africa
Urban Population / statistics & numerical data
Grant Support
ID/Acronym/Agency:
K01 AI083097/AI/NIAID NIH HHS; K01AI083097/AI/NIAID NIH HHS; R01 HL090312/HL/NHLBI NIH HHS; R01HL090312/HL/NHLBI NIH HHS; U2RTW007370/3//PHS HHS; //PEPFAR
Chemical
Reg. No./Substance:
0/Anti-Retroviral Agents
Comments/Corrections

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