Document Detail

Rate and extent of recovery of left ventricular function in patients following acute myocardial infarction.
MedLine Citation:
PMID:  3307359     Owner:  NLM     Status:  MEDLINE    
To determine the rate and extent of recovery of left ventricular (LV) performance following acute myocardial infarction (MI), peak aortic blood acceleration was measured serially in 26 patients and in 11 normal volunteers with a continuous wave Doppler placed suprasternally. In patients, Doppler measurements were made 20 +/- 2 hours after the acute onset of chest discomfort and were repeated daily for 6 consecutive days. Infarction patients were divided into two groups. Group I consisted of 15 patients who did not have a previous MI and whose present course was not complicated by congestive heart failure (CHF). Group II consisted of 11 patients who had either a previous MI or developed CHF during the present admission. Peak acceleration in the normal volunteers showed minimal daily variations over a period of 6 days. Peak acceleration in the entire group of 26 MI patients increased from 13 +/- 3 m/sec/sec on the day of admission (day 1) to 18 +/- 6 m/sec/sec on day 6 (p less than 0.001). In group I, peak acceleration increased from 13 +/- 4 to 20 +/- 6 m/sec/sec between day 1 and day 6 (p less than 0.001). In group II, however, peak acceleration was 12 +/- 2 m/sec/sec on day 1 and increased to only 15 +/- 4 m/sec/sec on day 6 (NS). These results indicate that LV performance, based upon peak acceleration of blood in the ascending aorta, improves markedly within 6 days in patients suffering their first MI uncomplicated by CHF.(ABSTRACT TRUNCATED AT 250 WORDS)
H N Sabbah; M Gheorghiade; S T Smith; D M Frank; P D Stein
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  American heart journal     Volume:  114     ISSN:  0002-8703     ISO Abbreviation:  Am. Heart J.     Publication Date:  1987 Sep 
Date Detail:
Created Date:  1987-09-29     Completed Date:  1987-09-29     Revised Date:  2006-02-27    
Medline Journal Info:
Nlm Unique ID:  0370465     Medline TA:  Am Heart J     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  516-24     Citation Subset:  AIM; IM    
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MeSH Terms
Aged, 80 and over
Aorta / physiopathology
Blood Flow Velocity
Heart / physiopathology*
Heart Ventricles
Middle Aged
Myocardial Infarction / physiopathology*
Reference Values
Time Factors

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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