| Rate of endometrial adenocarcinoma in women screened before and after implementation of the Bethesda 2001 reporting system. | |
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MedLine Citation:
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PMID: 18323269 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVE: To assess the impact of the recommendation of the 2001 Bethesda System to report all benign-appearing endometrial cells seen in women aged > or = 40 years on the frequency with which endometrial carcinomas are potentially detected as a consequence of Pap test reports that mention endometrial cells. STUDY DESIGN: We identified all women diagnosed with endometrial adenocarcinoma who also had a Pap test during the preceding 6 months. The search was performed for 3-year periods before and after the date of implementation of Bethesda 2001. RESULTS: Benign endometrial cells were reported for 589 women in the 3 years before Bethesda 2001 and for 3,810 women in the 3 following years. The number of endometrial malignancies found on follow-up in these women decreased from 8 in the 3 years before Bethesda 2001 to only 4 subsequently. The frequency of reporting atypical or malignant glandular cells, as well as the likelihood of finding endometrial malignancy on follow-up, did not significantly change. CONCLUSION: Despite a 6.5-fold rise in the frequency of reporting benign endometrial cells after Bethesda 2001, the frequency of subsequent diagnosis of endometrial malignancies did not in-crease. |
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Authors:
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Michael Thrall; Klint Kjeldahl; Kay Savik; H Evin Gulbahce; Stefan E Pambuccian |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Acta cytologica Volume: 52 ISSN: 0001-5547 ISO Abbreviation: Acta Cytol. Publication Date: 2008 Jan-Feb |
Date Detail:
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Created Date: 2008-03-07 Completed Date: 2008-04-29 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0370307 Medline TA: Acta Cytol Country: United States |
Other Details:
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Languages: eng Pagination: 1-7 Citation Subset: IM |
Affiliation:
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Department of Laboratory Medicine, School of Nursing, University of Minnesota, Minneapolisa 55455, USA. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adenocarcinoma
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diagnosis,
epidemiology*,
pathology Adult Aged Endometrial Neoplasms / diagnosis, epidemiology*, pathology Female Humans Vaginal Smears |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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