| Rate of discordant findings in bilateral temporal artery biopsy to diagnose giant cell arteritis. | |
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MedLine Citation:
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PMID: 19228656 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVE: To determine to what extent performing simultaneous bilateral temporal artery biopsies might increase the diagnostic sensitivity in giant cell arteritis (GCA). METHODS: In total 173 consecutive pathology reports of temporal artery biopsies were reviewed for histological findings by a single pathologist. The rate of discordance of biopsy results was calculated in patients with GCA. RESULTS: Biopsies were performed bilaterally and simultaneously in 132 cases; 51 had positive results. In 38 the biopsy was positive on both sides (concordant results), while in 13 patients only one side was positive (discordant results), reaching a discordance rate of 13/51=0.255. Therefore 12.7% of the patients (one-half of the discordance rate) could have been misdiagnosed as biopsy-negative had a biopsy been done only unilaterally in those 51 cases. CONCLUSION: These data suggest that performing bilateral temporal artery biopsies increases the diagnostic sensitivity of the procedure by up to 12.7%, compared to unilateral biopsies. |
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Authors:
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Gabriel S Breuer; Gideon Nesher; Ronit Nesher |
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Publication Detail:
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Type: Journal Article Date: 2009-02-17 |
Journal Detail:
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Title: The Journal of rheumatology Volume: 36 ISSN: 0315-162X ISO Abbreviation: J. Rheumatol. Publication Date: 2009 Apr |
Date Detail:
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Created Date: 2009-04-03 Completed Date: 2009-06-01 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 7501984 Medline TA: J Rheumatol Country: Canada |
Other Details:
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Languages: eng Pagination: 794-6 Citation Subset: IM |
Affiliation:
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Department of Internal Medicine, Rheumatology Service, Shaare-Zedek Medical Center, Hebrew University Medical School, PO Box 3235, Jerusalem, Israel 91031. gbreuer@szmc.org.il |
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| MeSH Terms | |
Descriptor/Qualifier:
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Biopsy* Giant Cell Arteritis* / diagnosis, pathology Humans Sensitivity and Specificity Temporal Arteries / pathology* |
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