Document Detail

Rate of aspartic acid racemization in bone.
MedLine Citation:
PMID:  9760098     Owner:  NLM     Status:  MEDLINE    
There are no reports on rates of amino acid racemization in bones. To investigate the possibility of estimating age by evaluating amino acid residue racemization in human bones, a heating experiment was performed and the rate of aspartic acid racemization was determined using the Arrhenius equation. Assuming an annual mean temperature of 15 degrees C, the rate constant (k) for aspartic acid racemization in bone was calculated, and the racemization rate at 15 degrees C k (y) was 4.1036 x 10(-9)--much lower than that of dentin. These results suggest that it is more difficult to accurately determine age by analyzing aspartic acid residues in bone than in dentin.
S Ohtani
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The American journal of forensic medicine and pathology     Volume:  19     ISSN:  0195-7910     ISO Abbreviation:  Am J Forensic Med Pathol     Publication Date:  1998 Sep 
Date Detail:
Created Date:  1998-12-21     Completed Date:  1998-12-21     Revised Date:  2011-02-02    
Medline Journal Info:
Nlm Unique ID:  8108948     Medline TA:  Am J Forensic Med Pathol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  284-7     Citation Subset:  IM    
Department of Forensic Medicine, Kanagawa Dental College, Yokosuka, Japan.
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MeSH Terms
Aspartic Acid / metabolism*
Chromatography, Gas
Chromatography, High Pressure Liquid
Collagen / chemistry
Hot Temperature
Humerus / metabolism*
Linear Models
Reg. No./Substance:
56-84-8/Aspartic Acid; 9007-34-5/Collagen

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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