Document Detail

Rate of allergic fungal etiology of chronic rhinosinusitis in Turkish population.
MedLine Citation:
PMID:  17926053     Owner:  NLM     Status:  MEDLINE    
The aim of this study is to investigate intranasal fungal incidence in Turkish patients with chronic rhinosinusitis (CRS). One hundred patients with CRS and 40 healthy subjects as a control group were included in the prospective study. Nasal lavage samples were investigated for the presence of fungus, using new culture techniques and histopathologic examination. Epidermal and intradermal hypersensitivity tests were used to find out fungal atopy. Levels of serum eosinophils, total IgE and presence of fungus-specific IgE were investigated in the blood samples. Quantitative parameters were analyzed using Pearson chi(2) test. Allergic fungal sinusitis (AFS) was diagnosed in 13 (13%) patients. There was no fungal growth in the control group. Eosinophilic mucin was detected in 94% of patients. Clinical and laboratory parameters of CRS were not significantly different in patient groups with or without intranasal fungi. As a result, fungal incidence was not as high as expected in Turkish patients with CRS. Furthermore, no significant correlation could be found between presence of intranasal fungus and type-1 hypersensitivity in patients with CRS.
Yusuf Hidir; Fuat Tosun; Mehmet Ali Saracli; Armagan Gunal; Mustafa Gulec; Sertac Yetiser
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Publication Detail:
Type:  Comparative Study; Journal Article     Date:  2007-10-10
Journal Detail:
Title:  European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery     Volume:  265     ISSN:  0937-4477     ISO Abbreviation:  Eur Arch Otorhinolaryngol     Publication Date:  2008 Apr 
Date Detail:
Created Date:  2008-02-26     Completed Date:  2008-08-19     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9002937     Medline TA:  Eur Arch Otorhinolaryngol     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  415-9     Citation Subset:  IM    
Department of ORL and HNS, Gulhane Military Medical Academy, Gulhane Medical School, Etlik, 06018 Ankara, Turkey.
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MeSH Terms
Aged, 80 and over
Chronic Disease
Fungi / isolation & purification*
Middle Aged
Mycoses / epidemiology,  microbiology*
Retrospective Studies
Rhinitis, Allergic, Perennial / complications,  epidemiology*,  microbiology
Sinusitis / complications,  epidemiology*,  microbiology
Turkey / epidemiology

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