Document Detail

Rash after treatment with anistreplase.
MedLine Citation:
PMID:  2223309     Owner:  NLM     Status:  MEDLINE    
A palpable purpura developed on the legs and lower abdomen of a woman of 54 five days after she was treated with anistreplase anisoylated plasminogen streptokinase activator complex (APSAC) for an acute myocardial infarction. Histological examination of a skin biopsy specimen taken 6 days after treatment showed leucocytoclastic vasculitis. The rash resolved within two weeks and there were no other complications.
N Burrows; R R Jones
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  British heart journal     Volume:  64     ISSN:  0007-0769     ISO Abbreviation:  Br Heart J     Publication Date:  1990 Oct 
Date Detail:
Created Date:  1990-12-10     Completed Date:  1990-12-10     Revised Date:  2009-11-18    
Medline Journal Info:
Nlm Unique ID:  0370634     Medline TA:  Br Heart J     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  289-90     Citation Subset:  AIM; IM    
Department of Dermatology, Ealing Hospital, Southall, Middlesex.
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MeSH Terms
Anistreplase / adverse effects*
Middle Aged
Myocardial Infarction / drug therapy
Purpura, Schoenlein-Henoch / chemically induced*,  pathology
Skin / pathology
Thrombolytic Therapy / adverse effects*
Reg. No./Substance:

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