| Rare sensory and autonomic disturbances associated with vitamin B12 deficiency. | |
| | |
MedLine Citation:
|
PMID: 19720386 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
Vitamin B12 deficiency is an important nutritional disorder causing neurological manifestations of myelopathy, neuropathy and dementia. Sub-acute combined degeneration (SCD) with involvement of the posterior columns in the cervical and thoracic cord is a common presentation of this disorder. In this case report, we describe a 43 year old woman with pernicious anemia and myelopathy with atypical clinical features. The patient presented with motor symptoms, a sensory level and bladder dysfunction. She had severe autonomic disturbances including an episode of unexplained bronchospasm, which has not been previously reported as a manifestation of vitamin B12 deficiency. We review the literature regarding these rarely reported features of vitamin B12 deficiency, and discuss aspects of management of this reversible condition. We emphasize the importance of awareness of autonomic disturbances in B12 deficient individuals. |
| | |
Authors:
|
Preeti Puntambekar; Maysaa M Basha; Imad T Zak; Ramesh Madhavan |
Related Documents
:
|
17943296 - Vacuolar degeneration affecting brain macrophages/microglia in variant cjd: a report on... 7428176 - An unusual case of mannosidosis with severe deficiency of acid mannosidase in leukocyte... 19177046 - Late vitamin k deficiency bleeding after intramuscular prophylaxis at birth: a case rep... 1614776 - Primary hemochromatosis in children: report of three newly diagnosed cases and review o... 12166296 - Laboratory ascertainment of cryptosporidium and local authority policies for investigat... 15216186 - The reality of a self-occluding pump head: case report. |
Publication Detail:
|
Type: Case Reports; Journal Article Date: 2009-08-31 |
Journal Detail:
|
Title: Journal of the neurological sciences Volume: 287 ISSN: 1878-5883 ISO Abbreviation: J. Neurol. Sci. Publication Date: 2009 Dec |
Date Detail:
|
Created Date: 2009-11-09 Completed Date: 2010-02-12 Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 0375403 Medline TA: J Neurol Sci Country: Netherlands |
Other Details:
|
Languages: eng Pagination: 285-7 Citation Subset: IM |
Affiliation:
|
Department of Neurology, Wayne State University School of Medicine/Detroit Medical Center, 4201 St Antoine, Detroit, MI 48201, United States. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Adult Anemia, Pernicious / etiology, metabolism Autonomic Nervous System Diseases / etiology*, pathology, physiopathology Bronchi / innervation, physiopathology Bronchial Spasm / etiology, physiopathology Female Humans Leg / innervation, physiopathology Magnetic Resonance Imaging Muscle, Skeletal / innervation, physiopathology Neural Pathways / metabolism, pathology, physiopathology Paraparesis / etiology, physiopathology Sensation Disorders / etiology, physiopathology Spinal Cord / metabolism, pathology, physiopathology Spinal Cord Diseases / etiology*, pathology, physiopathology Subacute Combined Degeneration / etiology*, pathology, physiopathology Sympathetic Nervous System / metabolism, pathology, physiopathology Treatment Outcome Urinary Bladder, Neurogenic / etiology, physiopathology Vitamin B 12 / administration & dosage Vitamin B 12 Deficiency / complications*, drug therapy |
| Chemical | |
Reg. No./Substance:
|
68-19-9/Vitamin B 12 |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Functional imaging studies of hyposmia in Parkinson's disease.
Next Document: Effects of growth factors on equine synovial fibroblasts seeded on synthetic scaffolds for avascular...