Document Detail

Rare involvement of submandibular gland by oral squamous cell carcinoma.
MedLine Citation:
PMID:  19360744     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: The true involvement of the submandibular gland in primary oral cancer seems quite uncommon. METHODS: We retrospectively reviewed the pathologic records of 342 patients with oral squamous cell carcinoma who underwent wide excision of primary oral cancer and simultaneous neck dissection from January 2000 to December 2003. RESULTS: Of the 383 submandibular glands, only 7 (1.8%) exhibited tumor involvement. Of them, 5 glands were involved by direct extension from the primary tumor. One gland showed local invasion from an adjacent involved lymph node in level I and 1 was from intraglandular lymph node metastasis. All of these 6 tumors with submandibular gland involvement were T4 disease (p = .0003) and the neck nodal status on each was more than N2b (p < .0001). CONCLUSION: The patients with early-stage oral squamous cell carcinoma with preoperative N0 neck may be candidates for preservation of the submandibular gland.
Tseng-Cheng Chen; Wu-Chia Lo; Jenq-Yuh Ko; Pei-Jen Lou; Tsung-Lin Yang; Cheng-Ping Wang
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Head & neck     Volume:  31     ISSN:  1097-0347     ISO Abbreviation:  Head Neck     Publication Date:  2009 Jul 
Date Detail:
Created Date:  2009-06-24     Completed Date:  2009-10-22     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8902541     Medline TA:  Head Neck     Country:  United States    
Other Details:
Languages:  eng     Pagination:  877-81     Citation Subset:  IM    
Department of Otolaryngology, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei, Taiwan.
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MeSH Terms
Aged, 80 and over
Carcinoma, Squamous Cell / mortality,  pathology*,  therapy
Cohort Studies
Middle Aged
Mouth Neoplasms / mortality,  pathology*,  therapy
Neoplasm Invasiveness
Neoplasm Staging
Retrospective Studies
Risk Factors
Submandibular Gland / pathology*
Young Adult

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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