Document Detail

Rare case of naso-oral fistula with extensive osteocartilaginous necrosis secondary to cocaine abuse: review of otorhinolaryngological presentations in cocaine addicts.
MedLine Citation:
PMID:  11027056     Owner:  NLM     Status:  MEDLINE    
We report what we believe to be only the 10th case of palatal necrosis secondary to cocaine abuse in a 33-year-old female patient. Extensive necrosis also involved the cartilaginous and bony septum and paranasal sinuses. Following exclusion of other mid-line destructive diseases her treatment involved saline douches and cessation of cocaine. She remains under review within the department with no evidence of progressive disease. We present a review of the other nine cases of palatal necrosis reported in the world literature and demonstrate a greater incidence in female users. The various presenting conditions of cocaine abuse encountered within the head and neck region by the otorhinolaryngologist are then discussed.
J Lancaster; A Belloso; C A Wilson; M McCormick
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Publication Detail:
Type:  Case Reports; Journal Article; Review    
Journal Detail:
Title:  The Journal of laryngology and otology     Volume:  114     ISSN:  0022-2151     ISO Abbreviation:  J Laryngol Otol     Publication Date:  2000 Aug 
Date Detail:
Created Date:  2000-10-19     Completed Date:  2000-10-19     Revised Date:  2005-11-16    
Medline Journal Info:
Nlm Unique ID:  8706896     Medline TA:  J Laryngol Otol     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  630-3     Citation Subset:  AIM; IM    
Department of Otolaryngology, Royal Liverpool University Hospital, UK.
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MeSH Terms
Cocaine-Related Disorders / complications*,  therapy
Nasal Septum / drug effects,  pathology
Nose Diseases / chemically induced*,  pathology,  therapy
Oral Fistula / chemically induced*,  pathology,  therapy
Osteonecrosis / chemically induced*,  therapy
Palate / drug effects,  pathology*
Respiratory Tract Fistula / chemically induced*,  therapy
Sodium Chloride
Reg. No./Substance:
7647-14-5/Sodium Chloride

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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