Document Detail

Rare association of antiphospholipid syndrome and Takayasu arteritis.
MedLine Citation:
PMID:  16575491     Owner:  NLM     Status:  MEDLINE    
The antiphospholipid syndrome (APS) is characterized by obstetric and thrombotic complications in the presence of antiphospholipid antibodies. It can happen in an isolated way or in association with diffuse connective tissue diseases, mainly systemic lupus erythematosus. The association of APS with Takayasu arteritis (TA) is rarely described in the literature. We described a case of primary APS in a female patient who developed obstruction in large-size arteries, in spite of the use of oral anticoagulant, and increase of erythrocyte sedimentation rate, suggesting TA. The favorable response to prednisone treatment and later to infliximab reinforced the diagnosis of TA. The present report illustrates the existence of APS associated to TA, whose recognition is very important once the therapeutic strategy is radically different.
Mittermayer B Santiago; Otávio Paz
Publication Detail:
Type:  Case Reports; Journal Article     Date:  2006-03-31
Journal Detail:
Title:  Clinical rheumatology     Volume:  26     ISSN:  0770-3198     ISO Abbreviation:  Clin. Rheumatol.     Publication Date:  2007 May 
Date Detail:
Created Date:  2007-04-03     Completed Date:  2007-06-26     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  8211469     Medline TA:  Clin Rheumatol     Country:  Belgium    
Other Details:
Languages:  eng     Pagination:  821-2     Citation Subset:  IM    
Escola Bahiana de Medicina e Saúde Pública, Núcleo de Reumatologia da Bahia no Hospital Santa Izabel, Salvador, Bahia, Brazil.
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MeSH Terms
Antiphospholipid Syndrome / complications*
Takayasu Arteritis / complications*,  diagnosis

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