Document Detail

Rapidly progressive osteoarthrosis of ochronotic origin. A pathologic study.
MedLine Citation:
PMID:  3389349     Owner:  NLM     Status:  MEDLINE    
A case of hip osteoarthrosis associated with ochronosis in a 65-year-old woman is reported. Characteristic features of both conditions were observed macroscopically and on light and electron microscopic examination. In the cartilage the pigment deposits were located on and between thick collagen fibrils. In the synovial membrane there were embedded packets of cartilage shards of which the collagen fibrils and pigment were phagocytosed, as well as calcified bone debris whose disaggregation might have explained the presence of some apatite deposits free of any underlying collagen structure. As also previously observed, the present case of ochronotic hip osteoarthrosis is remarkable for the minor osteophyte formation and for the inclusion of pigmented cartilage shards in the osteomedullar remodeled territory. It also demonstrates a collapse of the femoral head cortex presumably related to the rapid clinical and radiologic evolution. By the well-known origin of its chondropathy and by the pigment labeling of the cartilage, ochronotic arthropathy provides an almost experimental model for analyzing a broader problem, i.e., that of the various components of an osteoarthrotic remodeling.
R Lagier; C A Baud; D Lacotte; T Cunningham
Related Documents :
6973119 - Otological aspects of the earpit-deafness syndrome.
8484129 - Sternocostoclavicular hyperostosis.
3389349 - Rapidly progressive osteoarthrosis of ochronotic origin. a pathologic study.
21063139 - Anatomical variation of mental foramen. a case report.
11149969 - Chordoid glioma: a novel tumor of the third ventricle.
1481849 - Chondrodysplasia punctata: another possible x-linked recessive case.
11343859 - Mole gun--an unusual firearm, a case note.
9770069 - Unusual extracranial complications of otitis media in a young hiv patient: retropharyng...
7634699 - Chronic achilles tendinopathy. a survey of surgical and histopathologic findings.
Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  American journal of clinical pathology     Volume:  90     ISSN:  0002-9173     ISO Abbreviation:  Am. J. Clin. Pathol.     Publication Date:  1988 Jul 
Date Detail:
Created Date:  1988-08-05     Completed Date:  1988-08-05     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0370470     Medline TA:  Am J Clin Pathol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  95-102     Citation Subset:  AIM; IM    
Department of Pathology (Osteoarticular Unit), University of Geneva Medical School, Switzerland.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Bone Diseases / etiology*,  pathology
Cartilage, Articular / ultrastructure
Joint Diseases / etiology*,  pathology
Microscopy, Electron
Ochronosis / complications*,  metabolism
Synovial Membrane / ultrastructure

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Identification of viridans streptococci by three commercial systems.
Next Document:  Noninvasive assessment of skin iron content in hemodialysis patients. An index of parenchymal tissue...