Document Detail

Rapidly progressive glomerulonephritis in adults: clinical and histologic correlations.
MedLine Citation:
PMID:  699399     Owner:  NLM     Status:  MEDLINE    
The clinical and histological features of 43 patients with rapidly progressive glomerulonephritis were reviewed. All had extensive crescent formation in more than 50 per cent of glomeruli. Three distinct patterns of immunofluorescent staining were identified: linear, granular, and sparse staining. Electron microscopy was valuable in corroborating the results of immunofluorescence. The prognosis was poor, with no patient regaining normal renal function regardless of treatment. Significant differences were observed among patients categorized by immunofluorescent staining. Those with a linear pattern were younger and more commonly had hemoptysis. Patients with sparse immunofluorescent staining had better renal function at the time of presentation and a longer duration of illness.
K R McLeish; M N Yum; F C Luft
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Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Clinical nephrology     Volume:  10     ISSN:  0301-0430     ISO Abbreviation:  Clin. Nephrol.     Publication Date:  1978 Aug 
Date Detail:
Created Date:  1978-12-20     Completed Date:  1978-12-20     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0364441     Medline TA:  Clin Nephrol     Country:  GERMANY, WEST    
Other Details:
Languages:  eng     Pagination:  43-50     Citation Subset:  IM    
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MeSH Terms
Capillaries / immunology,  ultrastructure
Complement C3 / analysis
Glomerulonephritis / diagnosis*,  immunology,  pathology
Immunoglobulin G / analysis
Immunoglobulin M / analysis
Kidney Glomerulus / blood supply,  immunology
Middle Aged
Reg. No./Substance:
0/Complement C3; 0/Immunoglobulin G; 0/Immunoglobulin M

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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