Document Detail

Rapidly fatal necrotising fasciitis caused by Streptococcus pyogenes.
MedLine Citation:
PMID:  8157746     Owner:  NLM     Status:  MEDLINE    
AIMS: To describe the morbid anatomical and bacteriological features in a series of five cases of rapidly fatal Streptococcus pyogenes necrotising fasciitis. METHODS: Post mortem and bacteriological examinations were made of five patients dying within 48 hours from rapidly fatal necrotising fasciitis. RESULTS: All five cases died rapidly from a toxic Streptococcus toxin syndrome as a result of developing necrotising fasciitis following trivial injury. CONCLUSIONS: Necrotising fasciitis caused by Streptococcus pyogenes infection can be rapidly fatal. This is probably the result of a toxic shock syndrome. Rapid, early diagnosis and swift and probably empirical treatment is required to avoid a fatal outcome.
P M Donaldson; B Naylor; J W Lowe; D R Gouldesbrough
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Publication Detail:
Type:  Case Reports; Journal Article; Review    
Journal Detail:
Title:  Journal of clinical pathology     Volume:  46     ISSN:  0021-9746     ISO Abbreviation:  J. Clin. Pathol.     Publication Date:  1993 Jul 
Date Detail:
Created Date:  1994-05-16     Completed Date:  1994-05-16     Revised Date:  2010-09-13    
Medline Journal Info:
Nlm Unique ID:  0376601     Medline TA:  J Clin Pathol     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  617-20     Citation Subset:  AIM; IM    
Department of Clinical medicine, University of Leeds.
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MeSH Terms
Aged, 80 and over
Fasciitis / complications,  microbiology*,  pathology
Fatal Outcome
Shock, Septic / etiology
Streptococcal Infections*
Streptococcus pyogenes*

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