Document Detail

Rapidly deforming gastric carcinosarcoma with osteoblastic component: an autopsy case report.
MedLine Citation:
PMID:  22912559     Owner:  NLM     Status:  MEDLINE    
Carcinosarcomas are rare, malignant, biphasic tumors simultaneously comprising carcinoma and sarcoma in a single tumor. We present an extremely rare case of gastric carcinosarcoma with an osteoblastic component that drastically changed its shape within 2 mo. A 59-year-old male patient presented to the emergency outpatient unit with a complaint of black stool. Gastrointestinal endoscopy showed an ulcerated mass in the cardia of the lesser curvature of the stomach. Biopsy specimens revealed only adenocarcinoma. Two months later, the ulcerated lesion drastically changed its shape into an exophytic tumor. Total gastrectomy was performed. In the resected specimen, the gastric tumor contained both adenocarcinoma and sarcoma components with lace-like osteoid. The patient died 7 mo after the operation, and an autopsy was performed. In the autopsy, widespread metastases were present in the liver, lung, lymph nodes and peritoneum. In this report, we describe a case of gastric carcinosarcoma and presume its tumorigenesis based on the autopsy findings.
Hiroshi Yoshida; Noriyuki Tanaka; Naobumi Tochigi; Yoshio Suzuki
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  World journal of gastroenterology : WJG     Volume:  18     ISSN:  2219-2840     ISO Abbreviation:  World J. Gastroenterol.     Publication Date:  2012 Aug 
Date Detail:
Created Date:  2012-08-22     Completed Date:  2013-03-04     Revised Date:  2014-05-20    
Medline Journal Info:
Nlm Unique ID:  100883448     Medline TA:  World J Gastroenterol     Country:  China    
Other Details:
Languages:  eng     Pagination:  4064-8     Citation Subset:  IM    
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MeSH Terms
Carcinosarcoma / pathology*,  secondary,  surgery
Fatal Outcome
Liver Neoplasms / secondary*
Lung Neoplasms / secondary*
Lymphatic Metastasis
Middle Aged
Peritoneal Neoplasms / secondary*
Stomach Neoplasms / pathology*,  surgery

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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