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Rapidly Growing Complex Fibroadenoma With Surrounding Ductal Hyperplasia Mimics Breast Malignancy on Serial F-18 FDG PET/CT Imaging.
MedLine Citation:
PMID:  21637064     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
A 30-year-old woman was referred for an F-18 fluorodeoxyglucose (FDG) PET/CT to rule out lymphoma, and was found to have an incidental FDG-avid right breast nodule that grew significantly in size and FDG uptake on a subsequent scan, raising suspicion of a growing breast malignancy. Histologic evaluation showed a complex fibroadenoma with adenosis and surrounding ductal hyperplasia. Although variable F-18 FDG uptake in fibroadenomas has been described, a distinction between simple and complex fibroadenomas has not been made in the PET literature, even though complex fibroadenomas have a higher propensity to develop into malignancies. This case shows that a rapidly growing complex fibroadenoma can mimic a breast malignancy on serial F-18 FDG PET/CT scans, showing significant increase in both size and FDG-avidity on follow-up studies.
Authors:
William Makis; Anthony Ciarallo; Marc Hickeson; Vilma Derbekyan
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Clinical nuclear medicine     Volume:  36     ISSN:  1536-0229     ISO Abbreviation:  Clin Nucl Med     Publication Date:  2011 Jul 
Date Detail:
Created Date:  2011-06-03     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7611109     Medline TA:  Clin Nucl Med     Country:  United States    
Other Details:
Languages:  eng     Pagination:  576-9     Citation Subset:  IM    
Affiliation:
From the *Department of Nuclear Medicine, Brandon Regional Health Centre, Brandon, Canada; and †Department of Nuclear Medicine, Royal Victoria Hospital, McGill University Health Centre, Montreal, Quebec, Canada.
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