| Rapid suppression of Onchocerca volvulus transmission in two communities of the Southern Chiapas focus, Mexico, achieved by quarterly treatments with Mectizan. | |
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MedLine Citation:
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PMID: 18689630 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The impact of quarterly Mectizan (ivermectin) treatments on transmission, microfiladermia, and ocular lesions was evaluated in two formerly hyperendemic communities (Las Golondrinas and Las Nubes II) located in the main endemic focus for onchocerciasis in Southern Chiapas, Mexico. The data suggest that Onchocerca volvulus transmission has been suppressed after elimination of microfiladermia in these two communities. Increasing the frequency of Mectizan treatment to four times per year appears to have resulted in the rapid suppression of transmission in communities with residual transmission. |
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Authors:
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Mario A Rodríguez-Pérez; Miguel A Lutzow-Steiner; Aldo Segura-Cabrera; Cristian Lizarazo-Ortega; Alfredo Domínguez-Vázquez; Mauricio Sauerbrey; Frank Richards; Thomas R Unnasch; Hassan K Hassan; Raymundo Hernández-Hernández |
Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: The American journal of tropical medicine and hygiene Volume: 79 ISSN: 1476-1645 ISO Abbreviation: Am. J. Trop. Med. Hyg. Publication Date: 2008 Aug |
Date Detail:
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Created Date: 2008-08-11 Completed Date: 2008-09-04 Revised Date: 2010-09-22 |
Medline Journal Info:
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Nlm Unique ID: 0370507 Medline TA: Am J Trop Med Hyg Country: United States |
Other Details:
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Languages: eng Pagination: 239-44 Citation Subset: AIM; IM |
Affiliation:
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Centro de Biotecnología Genómica, Instituto Politécnico Nacional, Blvd. del Maestro esq. Elias Piña, Cd. Reynosa, Tamaulipas, Mexico. mrodriguez@ipn.mx |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Animals Drug Administration Schedule Filaricides / administration & dosage, therapeutic use* Humans Ivermectin / administration & dosage, therapeutic use* Mexico / epidemiology Onchocerca volvulus / drug effects* Onchocerciasis / epidemiology, prevention & control*, transmission Skin / parasitology |
| Chemical | |
Reg. No./Substance:
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0/Filaricides; 70288-86-7/Ivermectin |
| Comments/Corrections | |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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