| Rapid reversal of critical haemodynamic compromise with nitric oxide in a parturient with amniotic fluid embolism. | |
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MedLine Citation:
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PMID: 17337177 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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We describe a case of amniotic fluid embolism presenting as cardiovascular collapse during labour. After initial resuscitation and emergency caesarean section, the patient was transferred to the intensive care unit with profound hypoxaemia, a high inotropic drug requirement and severe coagulopathy. A transoesophageal echocardiogram demonstrated acute right ventricular overload, severe pulmonary artery hypertension and marked diastolic dysfunction of the left ventricle secondary to a dilated right ventricle. The introduction of nitric oxide at 40 ppm produced a dramatic improvement in her cardiorespiratory status. Mother and baby both survived with no apparent long term sequelae. |
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Authors:
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N J McDonnell; B O Chan; R W Frengley |
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Publication Detail:
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Type: Case Reports; Journal Article Date: 2007-03-06 |
Journal Detail:
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Title: International journal of obstetric anesthesia Volume: 16 ISSN: 0959-289X ISO Abbreviation: Int J Obstet Anesth Publication Date: 2007 Jul |
Date Detail:
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Created Date: 2007-06-12 Completed Date: 2007-08-28 Revised Date: 2008-05-30 |
Medline Journal Info:
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Nlm Unique ID: 9200430 Medline TA: Int J Obstet Anesth Country: Netherlands |
Other Details:
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Languages: eng Pagination: 269-73 Citation Subset: IM |
Affiliation:
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Department of Anaesthesia, Waikato Hospital, Hamilton, New Zealand. nolanvini@mac.com |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Analgesia, Epidural Anesthesia, General Apgar Score Blood Coagulation Tests Echocardiography, Transesophageal Embolism, Amniotic Fluid / physiopathology* Female Humans Hypertension, Pulmonary / drug therapy, etiology Infant, Newborn Male Nitric Oxide / therapeutic use* Pregnancy Shock / drug therapy*, etiology* |
| Chemical | |
Reg. No./Substance:
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10102-43-9/Nitric Oxide |
| Comments/Corrections | |
Comment In:
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Int J Obstet Anesth. 2008 Apr;17(2):189-90; author reply 190
[PMID:
18308557
]
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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