Document Detail

Rapid resolution of primary vulval adult Langerhans cell histiocytosis with very potent topical corticosteroids.
MedLine Citation:
PMID:  21332684     Owner:  NLM     Status:  In-Data-Review    
Langerhans cell histiocytosis is a rare idiopathic disorder with protean clinical presentations. Primary unifocal single-system disease of the vulva is even less common. We report a 62-year-old female patient presenting with an 18-month history of pruritus and burning of the vulva. Clinical examination of the vulva showed a tender nodule of the right labium minus. Histology confirmed Langerhans cell histiocytosis. Systemic involvement was excluded. Within 1 month the use of clobetasol propionate ointment led to resolution of both the patient's symptoms and the clinical appearance of the affected right labium minus. This resolution was maintained 12 months later.
Susan Foley; Katherine Panting; Hazel Bell; Niamh Leonard; Andrea Franks
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The Australasian journal of dermatology     Volume:  52     ISSN:  1440-0960     ISO Abbreviation:  Australas. J. Dermatol.     Publication Date:  2011 Feb 
Date Detail:
Created Date:  2011-02-21     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0135232     Medline TA:  Australas J Dermatol     Country:  Australia    
Other Details:
Languages:  eng     Pagination:  e8-e14     Citation Subset:  IM    
Copyright Information:
© 2009 The Authors. Australasian Journal of Dermatology © 2009 The Australasian College of Dermatologists.
Wirral University Teaching Hospital NHS Foundation Trust, The Wirral, The Royal Liverpool and Broadgreen University Hospitals NHS Trust, Liverpool, and Countess of Chester Hospital NHS Foundation Trust, Chester, United Kingdom.
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