Document Detail


Rapid periapical bone destruction during endodontic treatment of a patient with rheumatoid arthritis.
MedLine Citation:
PMID:  18793934     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Rheumatoid arthritis is an autoimmune disease with an unknown etiology. Azathioprine is an immunosuppressive drug that is used to treat rheumatoid arthritis. This case report describes the rapid periapical bone destruction that occurred during the endodontic treatment of a rheumatoid arthritis patient taking azathioprine and a corticosteroid. The cause of the rapid destruction is unclear. However, severe side effects can occur after administering azathioprine to rheumatoid arthritis patients. Therefore, dentists should check the patient's medical state thoroughly in order to prevent side effects when performing endodontic treatment.
Authors:
Won-Mann Oh; In-Nam Hwang; Ho-Hyun Son; Yun-Chan Hwang
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Publication Detail:
Type:  Case Reports; Journal Article     Date:  2008-08-23
Journal Detail:
Title:  Journal of endodontics     Volume:  34     ISSN:  1878-3554     ISO Abbreviation:  J Endod     Publication Date:  2008 Oct 
Date Detail:
Created Date:  2008-09-16     Completed Date:  2009-01-28     Revised Date:  2009-05-21    
Medline Journal Info:
Nlm Unique ID:  7511484     Medline TA:  J Endod     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1261-3     Citation Subset:  D    
Affiliation:
Department of Conservative Dentistry, School of Dentistry, Dental Science Research Institute, Chonnam National University, Gwangju, Korea.
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MeSH Terms
Descriptor/Qualifier:
Acute Disease
Alveolar Bone Loss / etiology*
Anti-Inflammatory Agents / therapeutic use
Antirheumatic Agents / therapeutic use
Arthritis, Rheumatoid / drug therapy*
Azathioprine / therapeutic use
Humans
Immunocompromised Host
Immunosuppressive Agents / therapeutic use
Male
Middle Aged
Periapical Diseases / etiology*
Pregnenediones / therapeutic use
Pulpectomy
Pulpitis / therapy
Root Canal Therapy / adverse effects*
Suppuration
Chemical
Reg. No./Substance:
0/Anti-Inflammatory Agents; 0/Antirheumatic Agents; 0/Immunosuppressive Agents; 0/Pregnenediones; 14484-47-0/deflazacort; 446-86-6/Azathioprine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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