| Rapid onset and dissipation of left atrial spontaneous echo contrast during percutaneous balloon mitral valvotomy. | |
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MedLine Citation:
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PMID: 9539475 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND: Thromboembolism after percutaneous balloon mitral valvotomy (PBMV) has been attributed to dislodement of preexisting thrombus during transseptal puncture and instrumentation of the left atrium. The occurrence of thromboembolic events after PBMV in the absence of demonstrable left atrial thrombus before PBMV suggests that thrombus might form during the procedure. Spontaneous echo contrast (SEC) is a swirling pattern of blood echogenicity that is a marker of blood stasis in the left atrium. Exacerbation of left atrial SEC during PBMV may be indicative of an increased thromboembolic risk. METHODS: Transesophageal echocardiography was performed during PBMV in 20 patients with mitral stenosis. Grades of severity of left atrial SEC [0 (nil) to 4+ (severe)] were allocated before and after each balloon inflation. RESULTS: Before PBMV, SEC was present in 17 patients. New SEC or increased severity of SEC was observed during 49 of 56 balloon inflations. SEC was unchanged after six deflations, decreased after 14 deflations, and disappeared after 36 deflations. The mean times to onset and dissipation of SEC after balloon inflation and deflation were 3.1+/-1.5 and 3.9+/-1.6 seconds, respectively. After successful PBMV, SEC was unchanged in three patients, decreased in one, and resolved in 13. CONCLUSIONS: SEC is a dynamic and acutely reversible phenomenon that is highly sensitive to changes in left atrial hemodynamic conditions. Left atrial blood stasis induced by balloon inflation may promote thrombogenesis during PBMV. |
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Authors:
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D Fatkin; P Roy; A Sindone; M Feneley |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: American heart journal Volume: 135 ISSN: 0002-8703 ISO Abbreviation: Am. Heart J. Publication Date: 1998 Apr |
Date Detail:
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Created Date: 1998-04-24 Completed Date: 1998-04-24 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0370465 Medline TA: Am Heart J Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 609-13 Citation Subset: AIM; IM |
Affiliation:
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Cardiology Department, St. Vincent's Hospital, Sydney, Australia. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aged Atrial Fibrillation / complications Atrial Flutter / complications Balloon Dilatation / adverse effects* Contrast Media* Echocardiography, Doppler Echocardiography, Transesophageal Female Heart Atria / physiopathology, ultrasonography* Humans Male Middle Aged Mitral Valve Stenosis / complications, therapy*, ultrasonography Rheumatic Heart Disease / complications, therapy, ultrasonography Risk Factors Severity of Illness Index Thromboembolism / etiology |
| Chemical | |
Reg. No./Substance:
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0/Contrast Media |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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