| Rapid lipid enrichment in omega3 fatty acids: liver data. | |
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MedLine Citation:
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PMID: 18288384 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The bolus intravenous injection of a novel medium-chain triglyceride:fish oil emulsion to normal subjects was recently reported to enrich within 60 min the phospholipid content of leucocytes and platelets in long-chain polyunsaturated omega3 fatty acids. The present study, conducted in second generation omega3-depleted rats, aims at investigating whether such a procedure may also increase within 60 min the phospholipid content of omega3 fatty acids in cells located outwards of the bloodstream, in this case liver cells, and whether this coincides with correction of the perturbation in the liver triglyceride fatty acid content and profile otherwise prevailing in these rats. The results indicate that such is indeed the case and further suggest a cause-to-effect relationship between the two events. |
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Authors:
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Yvon A Carpentier; Sebastien Peltier; Laurence Portois; Abdullah Sener; Willy J Malaisse |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: International journal of molecular medicine Volume: 21 ISSN: 1107-3756 ISO Abbreviation: Int. J. Mol. Med. Publication Date: 2008 Mar |
Date Detail:
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Created Date: 2008-02-21 Completed Date: 2008-04-22 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9810955 Medline TA: Int J Mol Med Country: Greece |
Other Details:
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Languages: eng Pagination: 367-73 Citation Subset: IM |
Affiliation:
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Laboratories of Experimental Hormonology and Surgery, Brussels Free University, Brussels, Belgium. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Animals Diglycerides / metabolism Fatty Acids, Omega-3 / metabolism* Female Fish Oils / metabolism Injections, Intravenous Liver / metabolism* Male Phospholipids / metabolism Plant Oils / metabolism Rats Triglycerides / metabolism |
| Chemical | |
Reg. No./Substance:
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0/Diglycerides; 0/Fatty Acids, Omega-3; 0/Fish Oils; 0/Phospholipids; 0/Plant Oils; 0/Triglycerides; 8001-25-0/olive oil |
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