| Rapid improvement in academic grades following methylphenidate treatment in attention-deficit hyperactivity disorder. | |
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MedLine Citation:
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PMID: 14678455 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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In the present study a 16 week comparison study was conducted of behavioral, cognitive and educational measures in school-age Taiwanese children with attention-deficit hyperactivity disorder (ADHD) receiving open-label methylphenidate (MPH). Subjects include 14 male and five female ADHD children. They received MPH twice per day continuously for 16 weeks. Measures of behavior, cognitive function (Wisconsin Card Sorting Test, Tower of London and Continuous Performance Test), Chinese and arithmetic learning achievement were compared with those of their baseline condition. After MPH, 68-78% of children showed improving behavior in classroom and at home. Among the neuropsychological tests, only the percentage of preservative error was improved (P = 0.022). Approximately 61-66% of children had improvement in academic learning (P = 0.013 for Chinese, 0.004 for arithmetic). The MPH treatment demonstrated improvement in domains of classroom/home behaviors and academic performance, but showed minimal change on neuropsychological functioning in Taiwanese ADHD children. The finding of academic gain was unexpected, which might be due to the greater interest in achievement and better compliance to cultural expectations by Taiwanese versus Western students, which translated into more rapid improvement in academic performance. |
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Authors:
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Pinchen Yang; Li-Chen Chung; Cheng-Sheng Chen; Cheng-Chung Chen |
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Publication Detail:
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Type: Clinical Trial; Comparative Study; Journal Article |
Journal Detail:
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Title: Psychiatry and clinical neurosciences Volume: 58 ISSN: 1323-1316 ISO Abbreviation: Psychiatry Clin. Neurosci. Publication Date: 2004 Feb |
Date Detail:
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Created Date: 2003-12-17 Completed Date: 2004-05-14 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 9513551 Medline TA: Psychiatry Clin Neurosci Country: Australia |
Other Details:
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Languages: eng Pagination: 37-41 Citation Subset: IM |
Affiliation:
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Department of Psychiatry, Kaohsiung Medical University Hospital, Taiwan. pichya@cc.kmu.edu.tw |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Administration, Oral Attention Deficit Disorder with Hyperactivity / complications, drug therapy*, ethnology Child Cognition / drug effects* Cultural Characteristics Educational Status Female Humans Male Methylphenidate / administration & dosage, pharmacology, therapeutic use* Patient Compliance Taiwan / ethnology Treatment Outcome |
| Chemical | |
Reg. No./Substance:
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113-45-1/Methylphenidate |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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