| Rapid identification of correctly located intracerebroventricular cannula in the rat. | |
| | |
MedLine Citation:
|
PMID: 6413786 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
We describe a radiographic technique to identify a correctly located cannula in the ventricular system of the rat brain during life. A suspension of thorium dioxide was infused into the left lateral ventricle through a cannula placed in the brain under stereotaxic guidance. Correctly located injections were identified by the presence of a distinct thorium shadow on lateral X-ray of the in situ brain. When 6-hydroxydopamine was co-injected with thorium the resultant depletion of striatal dopamine and the changes in a conditioned avoidance responses were correlated with the degree of spreading of thorium through the ventricular system. |
| | |
Authors:
|
M P Heyes; S Garnett; G Coates |
Related Documents
:
|
1481626 - The topography of microthrombi in ischemic brain infarct. 11099706 - Cobalt-55 positron emission tomography in late-onset epileptic seizures after thrombo-e... 11176306 - Mr perfusion studies of brain for patients with unilateral carotid stenosis or occlusio... 2782086 - Multiple idiopathic emboli in a full term neonate. 17157396 - Circulating angiogenic cytokines and stem cells in patients with severe chronic ischemi... 22487996 - Mild therapeutic hypothermia in cardiogenic shock syndrome. |
Publication Detail:
|
Type: Journal Article |
Journal Detail:
|
Title: Journal of neuroscience methods Volume: 8 ISSN: 0165-0270 ISO Abbreviation: J. Neurosci. Methods Publication Date: 1983 Aug |
Date Detail:
|
Created Date: 1983-11-23 Completed Date: 1983-11-23 Revised Date: 2003-11-14 |
Medline Journal Info:
|
Nlm Unique ID: 7905558 Medline TA: J Neurosci Methods Country: NETHERLANDS |
Other Details:
|
Languages: eng Pagination: 381-4 Citation Subset: IM |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
3,4-Dihydroxyphenylacetic Acid
/
analysis Animals Catheterization Cerebral Ventriculography / methods Corpus Striatum / analysis* Dopamine / analysis Hydroxydopamines / administration & dosage* Hypothalamus / analysis* Injections, Intraventricular / standards* Male Norepinephrine / analysis Oxidopamine Rats Rats, Inbred Strains Thorium Dioxide / administration & dosage* |
| Chemical | |
Reg. No./Substance:
|
0/Hydroxydopamines; 102-32-9/3,4-Dihydroxyphenylacetic Acid; 1199-18-4/Oxidopamine; 1314-20-1/Thorium Dioxide; 51-41-2/Norepinephrine |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: A molecular orbital treatment on the reactivity of some polycyclic aromatic hydrocarbon diol-epoxide...
Next Document: Storage and long-term use of human biopsy tissue in histochemical studies.