| Rapid computerized assessment of neurocognitive deficits in bipolar disorder. | |
| | |
MedLine Citation:
|
PMID: 20183173 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
The purpose of this study is to illustrate the clinical usefulness of a computerized neuropsychological battery for identifying neurocognitive deficits in adults with bipolar disorder. Participants were 47 outpatients with bipolar disorder who were individually matched on age, education, sex, and ethnicity to 47 control subjects from the Central Nervous System (CNS) Vital Signs normative database. CNS Vital Signs is comprised of seven common neuropsychological measures, and it generates 15 primary scores that are used to calculate five domain scores (Memory, Psychomotor Speed, Reaction Time, Cognitive Flexibility, and Complex Attention). There was a significant multivariate effect and statistically significantly worse scores for those in the bipolar group on all five domain scores (medium to large effect sizes). When using two or more scores below the fifth percentile as a cutoff for neurocognitive impairment, 42.6% of the bipolar sample and only 6.4% of the control sample scored in this range. A subset of outpatients with bipolar disorder has frank neurocognitive impairments identifiable with this 30-40-minute computerized assessment battery. |
| | |
Authors:
|
Grant L Iverson; Brian L Brooks; Allan H Young |
Related Documents
:
|
2149653 - The concept of distinct but voluminous groups of bipolar and unipolar diseases. ii. uni... 20488553 - Region and diagnosis-specific changes in synaptic proteins in schizophrenia and bipolar... 21714473 - Diagnosing and managing psychosis in primary care. |
Publication Detail:
|
Type: Journal Article |
Journal Detail:
|
Title: Applied neuropsychology Volume: 16 ISSN: 1532-4826 ISO Abbreviation: Appl Neuropsychol Publication Date: 2009 Jul |
Date Detail:
|
Created Date: 2010-02-25 Completed Date: 2010-05-12 Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 9507620 Medline TA: Appl Neuropsychol Country: United States |
Other Details:
|
Languages: eng Pagination: 207-13 Citation Subset: IM |
Affiliation:
|
Department of Psychiatry, University of British Columbia, Vancouver, BC, V6T 2A1,Canada. giverson@interchange.ubc.ca |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Adult Bipolar Disorder / complications* Cognition Disorders / diagnosis*, etiology* Female Humans Male Middle Aged Neuropsychological Tests* Numerical Analysis, Computer-Assisted* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: The provision of neuropsychological services in rural/regional settings: professional and ethical is...
Next Document: Serious Problems with the Mexican Norms for the WAIS-III when Assessing Mental Retardation in Capita...