Document Detail

Rapid right ventricular pacing with MR-compatible pacemaker lead for MR-guided aortic balloon valvuloplasty in swine.
MedLine Citation:
PMID:  20501717     Owner:  NLM     Status:  MEDLINE    
PURPOSE: To assess the feasibility and effectiveness of rapid right ventricular pacing with a magnetic resonance (MR)-compatible pacemaker lead during MR-guided aortic valvuloplasty.
MATERIALS AND METHODS: This study was approved by the institutional animal research committee. Seven pigs were investigated. All experiments were performed with an interventional 1.5-T MR system. Interventions were monitored with a steady-state free precession real-time imaging sequence. An MR-compatible pacemaker lead was placed in the right ventricular apex with MR guidance before valvuloplasty. After positioning the balloon in valve position, valvuloplasty was performed with rapid right ventricular rapid pacing at a heart rate of 180 beats per minute to minimize cardiac output.
RESULTS: Positioning of the pacemaker lead with MR guidance was feasible in all swine (sensing, 6 mV +/- 1; threshold, 1 V +/- 0.5). The lead could be seen on steady-state free precession images without inducing any artifacts. Rapid right ventricular pacing was feasible in all swine, and balloon stability at the time of inflation was achieved with no balloon movement. Aortic valvuloplasty was successfully accomplished in all experiments.
CONCLUSION: Rapid right ventricular pacing with an MR-compatible pacemaker lead is feasible and effective.
Mirja Neizel; Nils Krämer; Florian Bönner; Adrian Schütte; Sascha Krüger; Malte Kelm; Rolf W Günther; Harald P Kühl; Gabriele A Krombach
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Radiology     Volume:  255     ISSN:  1527-1315     ISO Abbreviation:  Radiology     Publication Date:  2010 Jun 
Date Detail:
Created Date:  2010-05-26     Completed Date:  2010-07-15     Revised Date:  2013-04-11    
Medline Journal Info:
Nlm Unique ID:  0401260     Medline TA:  Radiology     Country:  United States    
Other Details:
Languages:  eng     Pagination:  799-804     Citation Subset:  AIM; IM    
Copyright Information:
Copyright RSNA, 2010
Department of Cardiology, Angiology and Pulmonology, University Hospital Düsseldorf, Düsseldorf, Germany.
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MeSH Terms
Cardiac Pacing, Artificial / methods*
Contrast Media
Feasibility Studies
Heart Ventricles*
Magnetic Resonance Imaging, Interventional*
Magnetite Nanoparticles
Reg. No./Substance:
0/Contrast Media; 0/Magnetite Nanoparticles; 1317-61-9/Ferumoxytol; 9004-54-0/Dextrans; G6N3J05W84/ferumoxides

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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