Document Detail

Rapid, High-Resolution Electroanatomical Mapping: Evaluation of a New System in a Canine Atrial Linear Lesion Model.
MedLine Citation:
PMID:  22392447     Owner:  NLM     Status:  Publisher    
BACKGROUND: -A canine right atrial (RA) linear lesion model was used to produce a complex pattern of RA activation to evaluate a novel mapping system for rapid, high resolution (HR) electroanatomical mapping. METHODS AND RESULTS: -The mapping system (Rhythmia Medical, Inc) uses an 8F deflectable catheter with a mini-basket (1.8cm diameter), containing 8 splines of 8 electrodes (total 64 electrodes, 2.5mm spacing). The system automatically acquires electrograms and location information based on electrogram stability and respiration phase. In 10 anesthetized dogs, HR-RA map was obtained by maneuvering the mini-basket catheter during sinus rhythm and CS pacing. A right thoracotomy was performed and either one or two (to create a gap) epicardial linear lesions were created on the RA free-wall (surgical incision or epicardial radiofrequency lesions). RA maps during RA pacing close to the linear lesions were obtained. Total 73 maps were created with 44-729 (median 237) beats and 833-12,412 (median 3,589) electrograms (≤2-≤5mm from surface geometry), resolution 1.8-5.3 (median 2.7) mm, and 2.6-26.3 (median 7.3) min mapping time. Without manual annotation, the system accurately created RA geometry and demonstrated RA activation, identifying the location of lines of block and presence or absence of a gap in all 10 dogs. Endocardial radiofrequency catheter ablation of a gap (guided by activation map) produced complete block across the gap in all 3 dogs tested. CONCLUSIONS: -The new HR-mapping system accurately and quickly identifies geometry and complex patterns of activation in the canine RA with little or no manual annotation of activation time.
Hiroshi Nakagawa; Atsushi Ikeda; Tushar Sharma; Ralph Lazzara; Warren M Jackman
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-3-5
Journal Detail:
Title:  Circulation. Arrhythmia and electrophysiology     Volume:  -     ISSN:  1941-3084     ISO Abbreviation:  -     Publication Date:  2012 Mar 
Date Detail:
Created Date:  2012-3-6     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101474365     Medline TA:  Circ Arrhythm Electrophysiol     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
University of Oklahoma Health Sciences Center, Oklahoma City, OK.
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