| Rapid analysis of perchlorate in drinking water at parts per billion levels using microchip electrophoresis. | |
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MedLine Citation:
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PMID: 20334437 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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A microchip capillary electrophoresis (MCE) system has been developed for the determination of perchlorate in drinking water. The United States Environmental Protection Agency (USEPA) recently proposed a health advisory limit for perchlorate in drinking water of 15 parts per billion (ppb), a level requiring large, sophisticated instrumentation, such as ion chromatography coupled with mass spectrometry (IC-MS), for detection. An inexpensive, portable system is desired for routine online monitoring applications of perchlorate in drinking water. Here, we present an MCE method using contact conductivity detection for perchlorate determination. The method has several advantages, including reduced analysis times relative to IC, inherent portability, high selectivity, and minimal sample pretreatment. Resolution of perchlorate from more abundant ions was achieved using zwitterionic, sulfobetaine surfactants, N-hexadecyl-N,N-dimethyl-3-ammonio-1-propane sulfonate (HDAPS) and N-tetradecyl-N,N-dimethyl-3-ammonio-1-propane sulfonate (TDAPS). The system performance and the optimization of the separation chemistry, including the use of these surfactants to resolve perchlorate from other anions, are discussed in this work. The system is capable of detection limits of 3.4 +/- 1.8 ppb (n = 6) in standards and 5.6 +/- 1.7 ppb (n = 6) in drinking water. |
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Authors:
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Jana C Gertsch; Scott D Noblitt; Donald M Cropek; Charles S Henry |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Analytical chemistry Volume: 82 ISSN: 1520-6882 ISO Abbreviation: Anal. Chem. Publication Date: 2010 May |
Date Detail:
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Created Date: 2010-04-30 Completed Date: 2010-08-18 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0370536 Medline TA: Anal Chem Country: United States |
Other Details:
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Languages: eng Pagination: 3426-9 Citation Subset: IM |
Affiliation:
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Department of Chemistry, Colorado State University, Fort Collins, CO, USA. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Electrophoresis, Microchip
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methods* Perchloric Acid / chemistry* United States United States Environmental Protection Agency / standards Water Supply / analysis*, standards |
| Chemical | |
Reg. No./Substance:
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0/perchlorate; 7601-90-3/Perchloric Acid |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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