Document Detail


Ranolazine: focusing on angina pectoris.
MedLine Citation:
PMID:  16628259     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Chronic stable angina is common and is a difficult-to-manage problem when patients begin to fail conventional therapy especially when maximal revascularization has been provided. The most promising agent in development is ranolazine, a late sodium channel inhibitor and partial fatty oxidation inhibitor which has unique and desirable anti-ischemic and electrophysiologic properties. This agent is likely to become standard therapy for chronic stable angina and may play a future role in the management of acute coronary syndromes.
Authors:
Peter A McCullough
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Drugs of today (Barcelona, Spain : 1998)     Volume:  42     ISSN:  1699-3993     ISO Abbreviation:  Drugs Today     Publication Date:  2006 Mar 
Date Detail:
Created Date:  2006-04-21     Completed Date:  2006-08-18     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  101160518     Medline TA:  Drugs Today (Barc)     Country:  Spain    
Other Details:
Languages:  eng     Pagination:  177-83     Citation Subset:  IM    
Copyright Information:
Copyright 2006 Prous Science.
Affiliation:
Department of Medicine, Divisions of Cardiology, Nutrition and Preventive Medicine, William Beaumont Hospital, Royal Oak, Michigan 48073, USA. pmc975@yahoo.com
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MeSH Terms
Descriptor/Qualifier:
Acetanilides
Angina Pectoris / drug therapy*
Enzyme Inhibitors / therapeutic use
Humans
Piperazines / therapeutic use*
Randomized Controlled Trials as Topic
Chemical
Reg. No./Substance:
0/Acetanilides; 0/Enzyme Inhibitors; 0/Piperazines; 110445-25-5/ranolazine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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