Document Detail


Ranitidine in the treatment of acute upper gastrointestinal haemorrhage--a comparative study. Preliminary report.
MedLine Citation:
PMID:  6124495     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
50 patients with acute gastrointestinal bleeding (GIB) were randomly allocated to treatment with i.v. Ranitidine 50 mg b.d., or to a standard conservative therapy. When possible i.v. administration was replaced by oral ranitidine 150 mg b.d. for a total of up to 10 days. Three subgroups included gastric ulcer, duodenal ulcer and haemorrhagic gastritis. The criteria were: the need for blood replacement, comparison of the endoscopic appearance before and after therapy, and the final outcome of treatment, including the need for surgery. Ranitidine appeared to be superior to the standard treatment, the advantages being due largely to the gastric ulcer cases.
Authors:
A Nowak; C Sadliński; Z Górka; E Nowakowska; J Rudzki; K Gibiński
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Publication Detail:
Type:  Clinical Trial; Comparative Study; Journal Article; Randomized Controlled Trial    
Journal Detail:
Title:  Hepato-gastroenterology     Volume:  28     ISSN:  0172-6390     ISO Abbreviation:  Hepatogastroenterology     Publication Date:  1981 Oct 
Date Detail:
Created Date:  1982-09-10     Completed Date:  1982-09-10     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  8007849     Medline TA:  Hepatogastroenterology     Country:  GERMANY, WEST    
Other Details:
Languages:  eng     Pagination:  267-9     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Acute Disease
Adult
Aged
Anti-Ulcer Agents / therapeutic use
Clinical Trials as Topic
Duodenal Ulcer / drug therapy,  surgery
Female
Furans / therapeutic use*
Gastritis / drug therapy,  surgery
Gastrointestinal Hemorrhage / drug therapy*,  surgery
Histamine H2 Antagonists / therapeutic use
Humans
Male
Middle Aged
Peptic Ulcer Hemorrhage / drug therapy,  surgery
Ranitidine
Stomach Ulcer / drug therapy,  surgery
Chemical
Reg. No./Substance:
0/Anti-Ulcer Agents; 0/Furans; 0/Histamine H2 Antagonists; 66357-35-5/Ranitidine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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