Document Detail


Range of normal serum immunoglobulin (IgG, IgA and IgM) values in Nigerians.
MedLine Citation:
PMID:  6099979     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The serum levels of immunoglobulins G, A and M of 703 apparently healthy Nigerians resident in Ibadan and aged 1-50 years were studied. The differences in values that are related to age, sex and season were also computed. Normal values of the immunoglobulins varied with age and sex. IgG mean values for the different age groups ranged from 688 to 1251 mg/100 ml in the males and from 720 to 1038 mg/100 ml in the females. For the IgA class the mean values ranged from 81 to 211 mg/100 in the males and from 90 to 206 mg/100 ml in the females. Mean values of IgM varied from 65 to 132 mg/100 ml in the males and from 96 to 114 mg/100 ml in the females. There was a general increase in IgG levels with advancing age especially in the first 20 years of life. IgA increased progressively with age from 1 to 50 years. The male IgM levels generally rose with increasing age while there was no significant elevation in female IgM values. Females had higher levels of IgG, IgA and IgM in the first 10-20 years of life after which the levels were either the same or higher in the males. The possible reason for this observation is discussed. A significant seasonal influence on the three immunoglobulin concentrations could not be demonstrated.
Authors:
G O Oyeyinka; L S Salimonu; A I Williams; A O Johnson; O A Ladipo; B O Osunkoya
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  African journal of medicine and medical sciences     Volume:  13     ISSN:  0309-3913     ISO Abbreviation:  Afr J Med Med Sci     Publication Date:    1984 Sep-Dec
Date Detail:
Created Date:  1985-05-28     Completed Date:  1985-05-28     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  7801013     Medline TA:  Afr J Med Med Sci     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  169-76     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Age Factors
Child
Child, Preschool
Female
Humans
Immunoglobulin A / analysis
Immunoglobulin G / analysis
Immunoglobulin M / analysis
Immunoglobulins / analysis*
Infant
Male
Middle Aged
Nigeria
Reference Values
Seasons
Sex Factors
Chemical
Reg. No./Substance:
0/Immunoglobulin A; 0/Immunoglobulin G; 0/Immunoglobulin M; 0/Immunoglobulins

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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