Document Detail

Range of motion and adjacent level degeneration after lumbar total disc replacement.
MedLine Citation:
PMID:  16651217     Owner:  NLM     Status:  MEDLINE    
BACKGROUND CONTEXT: There are no published studies on the relationship between total disc replacement (TDR) motion and the development of adjacent level degeneration (ALD). Because prevention of ALD is the underlying justification for TDR, studies investigating the validity of this concept are essential. PURPOSE: To examine the relationship between range of motion (ROM) and ALD 8.7 years after lumbar TDR. STUDY DESIGN/SETTING: Retrospective radiographic and chart review. PATIENT SAMPLE: Forty-two patients 8.7 years after lumbar TDR. OUTCOME MEASURES: Radiographic flexion-extension and ALD. Modified Stauffer-Coventry score. Oswestry Disability Questionnaire. Subjective patient ratings of back pain, leg pain, and disability. METHODS: We reviewed the flexion-extension radiographs of 42 patients 8.7 years after TDR. Cephalad adjacent levels were evaluated for degeneration: loss of disc space height, anterior osteophyte formation, or dynamic flexion-extension instability. Graphical analysis of motion and the prevalence of ALD was performed. A statistical relationship between ALD and clinical outcome was sought. RESULTS: Ten of 42 patients evaluated (24%) had radiographic ALD. The mean motion was 3.8 degrees +/-2.0 degrees. The patients with ALD had mean motion of 1.6 degrees +/-1.3 degrees whereas the patients without ALD had motion of 4.7 degrees +/-4.5 degrees (p=.035). A clear relationship between motion and the presence of ALD at 8.7-year follow-up was observed. Patients with motion 5 degrees or greater (n=13) had a 0% prevalence of ALD. Patients with motion less than 5 degrees (n=29) had a 34% prevalence of ALD (p=.021, odds ratio 13.5). ALD had no statistically significant effect on clinical outcome although the sample size was small. CONCLUSIONS: At 8.7-year follow-up, the prevalence of ALD after TDR is higher in patients with motion less than 5 degrees. The presence of ALD had no significant effect on clinical outcome, but the sample size was small. These data suggest that patients with significant ROM after lumbar TDR may have reduced risk for radiographic ALD.
Russel C Huang; Patrick Tropiano; Thierry Marnay; Federico P Girardi; Moe R Lim; Frank P Cammisa
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The spine journal : official journal of the North American Spine Society     Volume:  6     ISSN:  1529-9430     ISO Abbreviation:  Spine J     Publication Date:    2006 May-Jun
Date Detail:
Created Date:  2006-05-02     Completed Date:  2006-07-05     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101130732     Medline TA:  Spine J     Country:  United States    
Other Details:
Languages:  eng     Pagination:  242-7     Citation Subset:  IM    
Spine Surgery Service, Hospital for Special Surgery, 535 East 70th Street, New York, NY 10021, USA.
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MeSH Terms
Arthroplasty, Replacement*
Intervertebral Disk / pathology*
Joint Diseases / surgery
Lumbar Vertebrae / pathology,  physiopathology*,  surgery
Middle Aged
Range of Motion, Articular*
Retrospective Studies
Spinal Diseases / surgery*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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