Document Detail

Randomized trials of rate vs. rhythm control for atrial fibrillation.
MedLine Citation:
PMID:  14739739     Owner:  NLM     Status:  MEDLINE    
Recent randomized trials have not demonstrated mortality or stroke risk reduction benefits from a rhythm-control compared to rate-control strategy in the treatment of atrial fibrillation. These studies reinforce the need for continued anticoagulation in both strategies for patients with atrial fibrillation and risk factors for stroke. Although rate control can be rationalized as a first line approach, rhythm control strategies may be justified for patients who are younger, who remain symptomatic or functionally impaired, or who have a first episode of atrial fibrillation.
Mina K Chung
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing     Volume:  10 Suppl 1     ISSN:  1383-875X     ISO Abbreviation:  J Interv Card Electrophysiol     Publication Date:  2004  
Date Detail:
Created Date:  2004-01-23     Completed Date:  2004-07-14     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  9708966     Medline TA:  J Interv Card Electrophysiol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  45-53     Citation Subset:  IM    
The Cleveland Clinic Foundation, Department of Cardiovascular Medicine, Section of Cardiac Electrophysiology and Pacing, Cleveland, Ohio 44195, USA.
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MeSH Terms
Anti-Arrhythmia Agents / therapeutic use
Anticoagulants / therapeutic use
Atrial Fibrillation / complications,  drug therapy,  physiopathology,  therapy*
Electric Countershock
Heart Rate
Randomized Controlled Trials as Topic
Stroke / prevention & control
Reg. No./Substance:
0/Anti-Arrhythmia Agents; 0/Anticoagulants

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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