Document Detail

Randomized trial of laser-assisted passage through occluded femoro-popliteal arteries.
MedLine Citation:
PMID:  2137717     Owner:  NLM     Status:  MEDLINE    
A randomized trial was carried out in patients with occlusions of the femoro-popliteal artery to compare the passage of metal-tipped optical fibres with guide wires and catheters through the occlusions, prior to balloon angioplasty. The study was in a provincial English teaching hospital providing a vascular service for the area. Fifty patients were entered; 25 into the "laser" group and 25 into the "control" group. End points were (a) the success in passage through the occlusion and (b) the outcome 1 month after passage. Comparison of the groups showed no appreciable difference between the two methods with regard to age, sex, symptoms, incidence of diabetes, or previous myocardial infarctions. Successful passage through the occlusion followed by dilatation was achieved in 18 (72%) patients in the laser group and 20 (80%) in the control group. After 1 month, 13 (52%) arteries in the laser group were patent compared to 13 (57%) in the control group. Confidence limits for the difference in success of passage are -15% to +31%, and -24% to +33% for patency after 1 month. Since these limits include zero, it is unlikely that a longer trial would alter the difference between the two methods. The results suggest that the laser system currently in use is no better than conventional methods.
W D Jeans; P Murphy; A O Hughes; M Horrocks; R N Baird
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Publication Detail:
Type:  Clinical Trial; Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  The British journal of radiology     Volume:  63     ISSN:  0007-1285     ISO Abbreviation:  Br J Radiol     Publication Date:  1990 Jan 
Date Detail:
Created Date:  1990-04-12     Completed Date:  1990-04-12     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  0373125     Medline TA:  Br J Radiol     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  19-21     Citation Subset:  AIM; IM    
Department of Radiodiagnosis, University of Bristol.
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MeSH Terms
Aged, 80 and over
Angioplasty, Balloon / methods*
Arterial Occlusive Diseases / therapy*
Femoral Artery*
Laser Therapy*
Middle Aged
Popliteal Artery*
Randomized Controlled Trials as Topic

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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