| Randomized trial of intracervical prostaglandin E2 gel and intraamniotic prostaglandin F2 alpha for induction of second trimester abortion. | |
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MedLine Citation:
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PMID: 6586395 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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For the purpose of reducing the side effects and complication rate when inducing second trimester abortion, intracervically administered PGE2 gel was tested for the first time and compared with a single intraamniotic instillation of PGF2 alpha by a randomized allocation of 41 consecutive patients in the 13th to 24th week of gestation. In both groups the treatment was supplemented with oxytocin 5 - 6 hours after starting the induction. The methods proved of equal value as regards the abortion success rate and the induction-abortion interval, whereas the incidence of gastrointestinal side effects on intracervical application of PGE2 gel was only half as high and the occurrence of diarrhea significantly lower (p less than 0.05) with this non-invasive method than with intraamniotic PGF2 alpha. Intracervical PGE2 gel also possessed other advantages, being int. al. more acceptable by the patients and technically easier to administer. |
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Authors:
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S Stampe Sørensen; P Wolf |
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Publication Detail:
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Type: Clinical Trial; Comparative Study; Journal Article; Randomized Controlled Trial |
Journal Detail:
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Title: Contraception Volume: 29 ISSN: 0010-7824 ISO Abbreviation: Contraception Publication Date: 1984 Feb |
Date Detail:
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Created Date: 1984-07-23 Completed Date: 1984-07-23 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0234361 Medline TA: Contraception Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 171-9 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Abortion, Induced* Adolescent Adult Amnion Cervix Uteri Dinoprost Dinoprostone Female Gels Humans Pregnancy Pregnancy Trimester, Second Prostaglandins E / administration & dosage*, adverse effects Prostaglandins F / administration & dosage*, adverse effects Random Allocation |
| Chemical | |
Reg. No./Substance:
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0/Gels; 0/Prostaglandins E; 0/Prostaglandins F; 363-24-6/Dinoprostone; 551-11-1/Dinoprost |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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