Document Detail

Randomized trial of different insufflation pressures for laparoscopic cholecystectomy.
MedLine Citation:
PMID:  9112891     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: The factors affecting cardiorespiratory changes and postoperative pain after laparoscopic cholecystectomy are poorly understood. The aim of this study was to assess these changes in patients undergoing laparoscopic cholecystectomy at an insufflation pressure of 7.5 or 15 mmHg. METHODS: Forty patients with similar preoperative characteristics were randomized, 20 to each group. RESULTS: There were no significant differences in intraoperative heart rate or cardiac index although the latter fell significantly soon after insufflation in both groups. The fall in cardiac index lasted longer (7 versus 2 min) and coincided with a slower rise in mean arterial pressure in those having 15 mmHg insufflation. Changes in peak airway pressure, end-tidal carbon dioxide and arterial blood gases were similar. After operation the low-pressure group had significantly less pain, better preservation of pulmonary function and were discharged home sooner (P = 0.015). CONCLUSIONS: Insufflation pressure significantly affects the haemodynamic changes and postoperative pain associated with laparoscopic cholecystectomy.
D H Wallace; M G Serpell; J N Baxter; P J O'Dwyer
Publication Detail:
Type:  Clinical Trial; Journal Article; Randomized Controlled Trial    
Journal Detail:
Title:  The British journal of surgery     Volume:  84     ISSN:  0007-1323     ISO Abbreviation:  Br J Surg     Publication Date:  1997 Apr 
Date Detail:
Created Date:  1997-05-21     Completed Date:  1997-05-21     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0372553     Medline TA:  Br J Surg     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  455-8     Citation Subset:  AIM; IM    
Department of Surgery, Western Infirmary, Glasgow, UK.
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MeSH Terms
Carbon Dioxide / analysis
Cholecystectomy, Laparoscopic / methods*
Forced Expiratory Volume
Heart Rate
Insufflation / standards*
Length of Stay
Middle Aged
Pain, Postoperative / prevention & control*
Vital Capacity
Reg. No./Substance:
124-38-9/Carbon Dioxide

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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