| Randomized controlled trial of percutaneous versus transcutaneous posterior tibial nerve stimulation in faecal incontinence. | |
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MedLine Citation:
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PMID: 23300071 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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BACKGROUND: Percutaneous, transcutaneous and sham transcutaneous posterior tibial nerve stimulation was compared in a prospective blinded randomized placebo-controlled trial. METHODS: Patients who had failed conservative treatment for faecal incontinence were randomized to one of three groups: group 1, percutaneous; group 2, transcutaneous; group 3, sham transcutaneous. Patients in groups 1 and 2 received 30-min sessions of posterior tibial nerve stimulation twice weekly for 6 weeks. In group 3, transcutaneous electrodes were placed in position but no stimulation was delivered. Symptoms were measured at baseline and after 6 weeks using a bowel habit diary and St Mark's continence score. Response to treatment was defined as a reduction of at least 50 per cent in weekly episodes of faecal incontinence compared with baseline. RESULTS: Thirty patients (28 women) were enrolled. Nine of 11 patients in group 1, five of 11 in group 2 and one of eight in group 3 had a reduction of at least 50 per cent in weekly episodes of faecal incontinence at the end of the 6-week study phase (P = 0·035). Patients undergoing percutaneous nerve stimulation had a greater reduction in the number of incontinence episodes and were able to defer defaecation for a longer interval than those undergoing transcutaneous and sham stimulation. These improvements were maintained over a 6-month follow-up period. CONCLUSION: Posterior tibial nerve stimulation has short-term benefits in treating faecal incontinence. Percutaneous therapy appears to have superior efficacy to stimulation applied by the transcutaneous route. Registration number: NCT00530933 (http://www.clinicaltrials.gov). Copyright © 2013 British Journal of Surgery Society Ltd. Published by John Wiley & Sons, Ltd. |
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Authors:
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A T George; K Kalmar; S Sala; K Kopanakis; A Panarese; T C Dudding; J R Hollingshead; R J Nicholls; C J Vaizey |
Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: The British journal of surgery Volume: 100 ISSN: 1365-2168 ISO Abbreviation: Br J Surg Publication Date: 2013 Feb |
Date Detail:
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Created Date: 2013-01-09 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0372553 Medline TA: Br J Surg Country: England |
Other Details:
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Languages: eng Pagination: 330-8 Citation Subset: AIM; IM |
Copyright Information:
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Copyright © 2013 British Journal of Surgery Society Ltd. Published by John Wiley & Sons, Ltd. |
Affiliation:
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Physiology Unit, St Mark's Hospital, Watford Road, Harrow HA1 3UJ, UK. anilthomasgeorge@hotmail.com. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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