| Randomized comparison of coronary stenting with balloon angioplasty in selected patients with acute myocardial infarction. | |
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MedLine Citation:
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PMID: 9657469 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND: Although the benefits of primary angioplasty in acute myocardial infarction have been demonstrated, several areas for improvement remain. Therefore, a prospective randomized trial comparing primary stenting with balloon angioplasty in patients with acute myocardial infarction was conducted. METHODS AND RESULTS: Patients with acute myocardial infarction were randomly assigned to undergo either primary stenting (n=112) or balloon angioplasty (n=115). The clinical end points were death, recurrent infarction, subsequent bypass surgery, or repeat angioplasty of the infarct-related vessel. The overall mortality rate at 6 months was 2%. Recurrent infarction occurred in 8 patients (7%) after balloon angioplasty and in 1 (1%) after stenting (P=0.036). Subsequent target-vessel revascularization was necessary in 19 (17%) and 4 (4%) patients, respectively (P=0.0016). The cardiac event-free survival rate in the stent group was significantly higher than in the balloon angioplasty group (95% versus 80%; P=0.012). CONCLUSIONS: In selected patients with acute myocardial infarction, primary stenting can be applied safely and effectively, resulting in a lower incidence of recurrent infarction and a significant reduction in the need for subsequent target-vessel revascularization compared with balloon angioplasty. |
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Authors:
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H Suryapranata; A W van 't Hof; J C Hoorntje; M J de Boer; F Zijlstra |
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Publication Detail:
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Type: Clinical Trial; Comparative Study; Journal Article; Randomized Controlled Trial |
Journal Detail:
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Title: Circulation Volume: 97 ISSN: 0009-7322 ISO Abbreviation: Circulation Publication Date: 1998 Jun |
Date Detail:
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Created Date: 1998-07-15 Completed Date: 1998-07-15 Revised Date: 2007-09-04 |
Medline Journal Info:
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Nlm Unique ID: 0147763 Medline TA: Circulation Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 2502-5 Citation Subset: AIM; IM |
Affiliation:
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Department of Cardiology, Hospital De Weezenlanden, Zwolle, The Netherlands. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Aged Angioplasty, Transluminal, Percutaneous Coronary* Coronary Angiography Female Humans Male Middle Aged Myocardial Infarction / radiography, therapy* Prospective Studies Risk Risk Factors Stents* Treatment Outcome |
| Comments/Corrections | |
Comment In:
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Circulation. 1998 Jun 30;97(25):2482-5
[PMID:
9657464
]
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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