Document Detail

Randomized comparison of coronary stenting with balloon angioplasty in selected patients with acute myocardial infarction.
MedLine Citation:
PMID:  9657469     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Although the benefits of primary angioplasty in acute myocardial infarction have been demonstrated, several areas for improvement remain. Therefore, a prospective randomized trial comparing primary stenting with balloon angioplasty in patients with acute myocardial infarction was conducted. METHODS AND RESULTS: Patients with acute myocardial infarction were randomly assigned to undergo either primary stenting (n=112) or balloon angioplasty (n=115). The clinical end points were death, recurrent infarction, subsequent bypass surgery, or repeat angioplasty of the infarct-related vessel. The overall mortality rate at 6 months was 2%. Recurrent infarction occurred in 8 patients (7%) after balloon angioplasty and in 1 (1%) after stenting (P=0.036). Subsequent target-vessel revascularization was necessary in 19 (17%) and 4 (4%) patients, respectively (P=0.0016). The cardiac event-free survival rate in the stent group was significantly higher than in the balloon angioplasty group (95% versus 80%; P=0.012). CONCLUSIONS: In selected patients with acute myocardial infarction, primary stenting can be applied safely and effectively, resulting in a lower incidence of recurrent infarction and a significant reduction in the need for subsequent target-vessel revascularization compared with balloon angioplasty.
H Suryapranata; A W van 't Hof; J C Hoorntje; M J de Boer; F Zijlstra
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Publication Detail:
Type:  Clinical Trial; Comparative Study; Journal Article; Randomized Controlled Trial    
Journal Detail:
Title:  Circulation     Volume:  97     ISSN:  0009-7322     ISO Abbreviation:  Circulation     Publication Date:  1998 Jun 
Date Detail:
Created Date:  1998-07-15     Completed Date:  1998-07-15     Revised Date:  2007-09-04    
Medline Journal Info:
Nlm Unique ID:  0147763     Medline TA:  Circulation     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  2502-5     Citation Subset:  AIM; IM    
Department of Cardiology, Hospital De Weezenlanden, Zwolle, The Netherlands.
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MeSH Terms
Angioplasty, Transluminal, Percutaneous Coronary*
Coronary Angiography
Middle Aged
Myocardial Infarction / radiography,  therapy*
Prospective Studies
Risk Factors
Treatment Outcome
Comment In:
Circulation. 1998 Jun 30;97(25):2482-5   [PMID:  9657464 ]

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