Document Detail


Randomized clinical trial of self-gripping mesh versus sutured mesh for Lichtenstein hernia repair.
MedLine Citation:
PMID:  23203909     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND: Many patients develop discomfort after open repair of a groin hernia. It was hypothesized that suture fixation of the mesh is a cause of these symptoms.
METHODS: This patient- and assessor-blinded randomized multicentre clinical trial compared a self-gripping mesh (Parietene Progrip(®)) and sutured mesh for open primary repair of uncomplicated inguinal hernia by the Lichtenstein technique. Patients were assessed before surgery, on the day of operation, and at 1 and 12 months after surgery. The primary endpoint was moderate or severe symptoms after 12 months, including a combination of chronic pain, numbness and discomfort.
RESULTS: The intention-to-treat population comprised 163 patients with self-gripping mesh and 171 with sutured mesh. The 12-month prevalence of moderate or severe symptoms was 17·4 and 20·2 per cent respectively (P = 0·573). There were no significant differences between the groups in postoperative complications (33·7 versus 40·4 per cent; P = 0·215), rate of recurrent hernia within 1 year (1·2 per cent in both groups) or quality of life.
CONCLUSION: The avoidance of suture fixation using a self-gripping mesh was not accompanied by a reduction in chronic symptoms after inguinal hernia repair.
REGISTRATION NUMBER: NCT00815698 (http://www.clinicaltrials.gov).
Authors:
L N Jorgensen; T Sommer; S Assaadzadeh; L Strand; A Dorfelt; M Hensler; J Rosenberg;
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Publication Detail:
Type:  Comparative Study; Journal Article; Multicenter Study; Randomized Controlled Trial     Date:  2012-11-30
Journal Detail:
Title:  The British journal of surgery     Volume:  100     ISSN:  1365-2168     ISO Abbreviation:  Br J Surg     Publication Date:  2013 Mar 
Date Detail:
Created Date:  2013-02-04     Completed Date:  2013-04-04     Revised Date:  2014-07-31    
Medline Journal Info:
Nlm Unique ID:  0372553     Medline TA:  Br J Surg     Country:  England    
Other Details:
Languages:  eng     Pagination:  474-81     Citation Subset:  AIM; IM    
Copyright Information:
Copyright © 2012 British Journal of Surgery Society Ltd. Published by John Wiley & Sons, Ltd.
Data Bank Information
Bank Name/Acc. No.:
ClinicalTrials.gov/NCT00815698
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MeSH Terms
Descriptor/Qualifier:
Acute Pain / etiology
Adolescent
Adult
Aged
Aged, 80 and over
Groin
Hernia, Inguinal / surgery*
Herniorrhaphy / methods*
Humans
Length of Stay
Male
Middle Aged
Pain, Postoperative / etiology
Patient Satisfaction
Postoperative Complications / etiology
Quality of Life
Surgical Mesh*
Suture Techniques*
Treatment Outcome
Young Adult
Investigator
Investigator/Affiliation:
C Hauge / ; L M Andersen / ; F Micheelsen /
Comments/Corrections
Comment In:
Br J Surg. 2013 Oct;100(11):1539   [PMID:  24037579 ]
Br J Surg. 2013 Oct;100(11):1539   [PMID:  24037578 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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