Document Detail

Randomized clinical trial of different bandage regimens after foam sclerotherapy for varicose veins.
MedLine Citation:
PMID:  20306530     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: This trial compared outcomes after foam sclerotherapy in patients wearing compression bandaging for 24 h or 5 days after treatment.
METHODS: Consecutive patients with primary uncomplicated varicose veins were randomized after foam sclerotherapy treatment. The primary endpoint was 6-week Aberdeen Varicose Vein Severity Score (AVVSS) and Burford pain score.
RESULTS: Some 124 legs were randomized, 61 to 24 h and 63 to 5 days of bandaging. Target vein occlusion rates at 6-week duplex imaging were 90 and 89 per cent respectively (P = 0.842). There was no significant difference in phlebitis after 2 weeks (P = 0.445) or skin discoloration after 6 weeks (46 versus 40 per cent; P = 0.546). There was no significant difference in the change in AVVSS from baseline to 2 weeks (-0.29 versus -0.80; P = 0.717) or to 6 weeks (-5.89 versus -5.14; 95 per cent confidence interval (c.i.) for the difference -3.29 to 1.80; P = 0.563), or in change in Burford pain score from baseline to 2 weeks (-9.04 versus -2.80; P = 0.248) or to 6 weeks (-17.32 versus -8.46; 95 per cent c.i. for the difference -19.06 to 1.33; P = 0.088), or in change in Short Form 36 score from baseline to 6 weeks (2.02 versus 1.74; P = 0.903).
CONCLUSION: There was no advantage to compression bandaging for more than 24 h when thromboembolus deterrent stockings were worn for the remainder of 14 days.
J L O'Hare; J Stephens; D Parkin; J J Earnshaw
Publication Detail:
Type:  Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  The British journal of surgery     Volume:  97     ISSN:  1365-2168     ISO Abbreviation:  Br J Surg     Publication Date:  2010 May 
Date Detail:
Created Date:  2010-04-15     Completed Date:  2010-05-05     Revised Date:  2014-07-30    
Medline Journal Info:
Nlm Unique ID:  0372553     Medline TA:  Br J Surg     Country:  England    
Other Details:
Languages:  eng     Pagination:  650-6     Citation Subset:  AIM; IM    
Copyright Information:
Copyright 2010 British Journal of Surgery Society Ltd.
Data Bank Information
Bank Name/Acc. No.:
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Aged, 80 and over
Follow-Up Studies
Middle Aged
Phlebitis / etiology
Sclerosing Solutions / therapeutic use
Sclerotherapy / methods*
Stockings, Compression
Treatment Outcome
Varicose Veins / therapy*
Reg. No./Substance:
0/Sclerosing Solutions

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Response to induction therapy in oesophageal and cardia carcinoma using Mandard tumour regression gr...
Next Document:  Obesity and gastrointestinal cancer.