Document Detail


Randomized clinical trial comparing endovenous laser with cryostripping for great saphenous varicose veins.
MedLine Citation:
PMID:  18763255     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND: The aim of this randomized single-centre trial was to compare the 2-year results of endovenous laser ablation (EVLA) and cryostripping for varicose veins. METHODS: A total of 120 patients with uncomplicated great saphenous varicose veins were randomized equally to one of the two treatments. Principal outcomes measures were: freedom from recurrent varicose veins on duplex imaging, and improvement in Venous Clinical Severity Score (VCSS) and Aberdeen Varicose Vein Severity Score (AVVSS) 6, 12 and 24 months after treatment. RESULTS: Life-table analysis showed overall freedom from recurrent incompetence at 2 years in 77 (95 per cent confidence interval (c.i.) 72 to 78) per cent of patients after EVLA and in 66 (95 per cent c.i. 60 to 67) per cent after cryostripping (P = 0.253). VCSS and AVVSS values improved significantly after treatment, but the differences between the treatments were not significant. EVLA provided significantly more favourable results than cryostripping with respect to duration of operation, postprocedural pain, induration and resumption of normal activity. CONCLUSION: EVLA and cryostripping were similarly effective in patients with varicose veins, but patients favoured EVLA because of less pain and postoperative morbidity, and quicker return to normal activity. Registration number: ISRCTN33832691 (http://www.controlled-trials.com).
Authors:
B C V M Disselhoff; D J der Kinderen; J C Kelder; F L Moll
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Publication Detail:
Type:  Comparative Study; Journal Article; Randomized Controlled Trial    
Journal Detail:
Title:  The British journal of surgery     Volume:  95     ISSN:  1365-2168     ISO Abbreviation:  Br J Surg     Publication Date:  2008 Oct 
Date Detail:
Created Date:  2008-09-08     Completed Date:  2008-09-25     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0372553     Medline TA:  Br J Surg     Country:  England    
Other Details:
Languages:  eng     Pagination:  1232-8     Citation Subset:  AIM; IM    
Affiliation:
Department of Surgery, Mesos Medical Centre, Utrecht, The Netherlands.
Data Bank Information
Bank Name/Acc. No.:
ISRCTN/ISRCTN33832691
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MeSH Terms
Descriptor/Qualifier:
Adult
Aged
Cryosurgery / methods*
Female
Humans
Laser Coagulation / methods*
Male
Middle Aged
Neovascularization, Pathologic / etiology
Postoperative Complications / etiology
Recurrence
Saphenous Vein / surgery*
Sclerotherapy / methods
Treatment Outcome
Varicose Veins / surgery*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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