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A Randomized Trial of Aerobic versus Resistance Exercise in Prostate Cancer Survivors.
MedLine Citation:
PMID:  23238110     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Androgen deprivation therapy (ADT) for prostate cancer (PCa) has side effects that significantly impair health-related quality of life (HRQOL). Exercise ameliorates many side effects of ADT but different modalities, particularly in the home-based setting, have not been well-studied. In this study we randomly assigned 66 PCa survivors receiving ADT to 6 months of home-based aerobic or resistance training. Psychosocial wellbeing and physical fitness were measured at baseline, 3 and 6 months, and then 6 months post-intervention. Intention-to-treat analyses showed that fatigue and HRQOL were not significantly different between groups; however, in a per-protocol analysis the resistance exercise training group demonstrated clinically significant improvements in HRQOL. Differential within-groups effects on physical fitness were also observed at various time-points. At all time-points, the aerobic training group engaged in significantly more physical activity than the resistance training group; a finding that should be further examined given evidence-based guidelines for activity volume in cancer survivors.
Authors:
Daniel Santa Mina; M H Alibhai S; Andrew G Matthew; Crissa L Guglietti; Meysam Pirbaglou; John Trachtenberg; Paul Ritvo
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-12-10
Journal Detail:
Title:  Journal of aging and physical activity     Volume:  -     ISSN:  1543-267X     ISO Abbreviation:  J Aging Phys Act     Publication Date:  2012 Dec 
Date Detail:
Created Date:  2012-12-14     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9415639     Medline TA:  J Aging Phys Act     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Affiliation:
Kinesiology Program, University of Guelph-Humber, Toronto, the Department of Surgical Oncology, Princess Margaret Hospital, Toronto, and the School of Kinesiology and Health Science, York University, Toronto, Ontario.
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