Document Detail

A Randomized Double Blind Cross-Over Study of Indoor Air Filtration and Acute Changes in Cardiorespiratory Health in a First Nations Community.
MedLine Citation:
PMID:  23210563     Owner:  NLM     Status:  Publisher    
Few studies have examined indoor air quality in First Nations communities and its impact on cardiorespiratory health. To address this need, we conducted a cross-over study on a First Nations reserve in Manitoba, Canada including 37 residents in 20 homes. Each home received an electrostatic air filter and a placebo filter for 1-week in random order and lung function, blood pressure, and endothelial function measures were collected at the beginning and end of each week. Indoor air pollutants were monitored throughout the study period. Indoor PM(2.5) decreased substantially during air filter weeks relative to placebo (mean difference: 37 μg/m(3) , 95% CI: 10, 64) but remained approximately 5-times greater than outdoor concentrations owing to a high prevalence of indoor smoking. On average, air filter use was associated with a 217 ml (95% CI: 23, 410) increase in forced expiratory volume in 1 second, a 7.9 mm Hg (95% CI:-17, 0.82) decrease in systolic blood pressure, and a 4.5 mm Hg (95% CI: -11, 2.4) decrease in diastolic blood pressure. Consistent inverse associations were also observed between indoor PM(2.5) and lung function. In general, our findings suggest that reducing indoor PM(2.5) may contribute to improved lung function in First Nations communities. © Her Majesty the Queen in Right of Canada 2012. Reproduced with the permission of the Minister of Health Canada.
Scott Weichenthal; Gary Mallach; Ryan Kulka; Andrew Black; Amanda Wheeler; Hongyu You; Melissa St-Jean; Roy Kwiatkowski; Donald Sharp
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-12-5
Journal Detail:
Title:  Indoor air     Volume:  -     ISSN:  1600-0668     ISO Abbreviation:  Indoor Air     Publication Date:  2012 Dec 
Date Detail:
Created Date:  2012-12-5     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9423515     Medline TA:  Indoor Air     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
© Her Majesty the Queen in Right of Canada 2012. Reproduced with the permission of the Minister of Health Canada.
Health Canada, Ottawa, Canada.
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