Document Detail


A randomized controlled trial of behavioral weight loss treatment versus combined weight loss/depression treatment among women with comorbid obesity and depression.
MedLine Citation:
PMID:  20878292     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND: Obesity is associated with clinical depression among women. However, depressed women are often excluded from weight loss trials.
PURPOSE: This study examined treatment outcomes among women with comorbid obesity and depression.
METHODS: Two hundred three (203) women were randomized to behavioral weight loss (n = 102) or behavioral weight loss combined with cognitive-behavioral depression management (n = 101).
RESULTS: Average participant age was 52 years; mean baseline body mass index was 39 kg/m(2). Mean Patient Health Questionnaire and Hopkins Symptom Checklist (SCL-20) scores indicated moderate to severe baseline depression. Weight loss and SCL-20 changes did not differ between groups at 6 or 12 months in intent-to-treat analyses (p = 0.26 and 0.55 for weight, p = 0.70 and 0.25 for depressive symptoms).
CONCLUSIONS: Depressed obese women lost weight and demonstrated improved mood in both treatment programs. Future weight loss trials are encouraged to enroll depressed women.
Authors:
Jennifer A Linde; Gregory E Simon; Evette J Ludman; Laura E Ichikawa; Belinda H Operskalski; David Arterburn; Paul Rohde; Emily A Finch; Robert W Jeffery
Publication Detail:
Type:  Journal Article; Randomized Controlled Trial; Research Support, N.I.H., Extramural    
Journal Detail:
Title:  Annals of behavioral medicine : a publication of the Society of Behavioral Medicine     Volume:  41     ISSN:  1532-4796     ISO Abbreviation:  Ann Behav Med     Publication Date:  2011 Feb 
Date Detail:
Created Date:  2011-01-31     Completed Date:  2011-05-10     Revised Date:  2012-02-02    
Medline Journal Info:
Nlm Unique ID:  8510246     Medline TA:  Ann Behav Med     Country:  United States    
Other Details:
Languages:  eng     Pagination:  119-30     Citation Subset:  IM    
Affiliation:
University of Minnesota, Minneapolis, USA. linde074@umn.edu
Data Bank Information
Bank Name/Acc. No.:
ClinicalTrials.gov/NCT00169273
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MeSH Terms
Descriptor/Qualifier:
Adult
Behavior Therapy / methods*
Body Mass Index
Comorbidity
Depression / psychology
Depressive Disorder, Major / epidemiology,  psychology*,  therapy
Female
Humans
Idaho / epidemiology
Middle Aged
Obesity / epidemiology,  psychology*,  therapy
Treatment Outcome
Washington / epidemiology
Weight Loss
Grant Support
ID/Acronym/Agency:
R01 MH068127-05/MH/NIMH NIH HHS; R01MH068127/MH/NIMH NIH HHS

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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