Document Detail


Randomized clinical trials in stroke research.
MedLine Citation:
PMID:  20009954     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
A randomized clinical trial is widely regarded as the most rigorous study design to determine the efficacy of intervention because spurious causality and bias associated with other experimental designs can be avoided. The purpose of this article is to provide clinicians and clinical researchers the types of randomized clinical trials used in stroke studies and to discuss the advantages and the limitations for each type of randomized stroke clinical trials.
Authors:
Chul Ahn; Daniel Ahn
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Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Extramural; Review    
Journal Detail:
Title:  Journal of investigative medicine : the official publication of the American Federation for Clinical Research     Volume:  58     ISSN:  1708-8267     ISO Abbreviation:  J. Investig. Med.     Publication Date:  2010 Feb 
Date Detail:
Created Date:  2010-02-04     Completed Date:  2010-04-16     Revised Date:  2011-07-22    
Medline Journal Info:
Nlm Unique ID:  9501229     Medline TA:  J Investig Med     Country:  Canada    
Other Details:
Languages:  eng     Pagination:  277-81     Citation Subset:  IM    
Affiliation:
Department of Clinical Sciences, The University of Texas Southwestern Medical Center at Dallas, Dallas, TX 75390-9066, USA. chul.ahn@utsouthwestern.edu
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MeSH Terms
Descriptor/Qualifier:
Cluster Analysis
Cross-Over Studies
Humans
Informed Consent
Mathematical Concepts
Random Allocation
Randomized Controlled Trials as Topic / methods*,  statistics & numerical data
Stroke / therapy*
Grant Support
ID/Acronym/Agency:
UL1 RR024982/RR/NCRR NIH HHS; UL1 RR024982-03/RR/NCRR NIH HHS
Comments/Corrections

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