Document Detail

Randomised trial of safety and efficacy of postoperative enteral feeding in patients with severe pancreatitis: preliminary report.
MedLine Citation:
PMID:  10881949     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: To find out whether postoperative enteral feeding is safe and effective in patients with severe pancreatitis. DESIGN: Prospective randomised trial. SETTING: Teaching hospital, Latvia. SUBJECTS: 29 patients who had been operated on for severe pancreatitis. INTERVENTIONS: They were randomised to have either enteral nutrition and conventional intravenous fluids postoperatively (n = 11), or conventional intravenous fluids only (n = 18). 17 additional patients who had had major abdominal operations for other conditions were also given enteral nutrition and intravenous fluids and comprised the control group. MAIN OUTCOME MEASURES: Nutritional intake, duration of stay in intensive care (ICU) and hospital morbidity, mortality, and outcome. RESULTS: 1 patient died of the 11 given enteral nutrition combined with conventional intravenous fluids, compared with 5/18 given fluids only. The pattern of bowel transit in the fed group did not differ from that in the control group. CONCLUSION: Postoperative enteral nutrition seems to be safe and effective in patients with severe pancreatitis and may improve survival. Our results suggest that enteral and parenteral nutrition may complement each other in seriously ill patients.
G Pupelis; E Austrums; A Jansone; R Sprucs; H Wehbi
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Publication Detail:
Type:  Clinical Trial; Journal Article; Randomized Controlled Trial    
Journal Detail:
Title:  The European journal of surgery = Acta chirurgica     Volume:  166     ISSN:  1102-4151     ISO Abbreviation:  Eur J Surg     Publication Date:  2000 May 
Date Detail:
Created Date:  2000-12-01     Completed Date:  2000-12-01     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  9105264     Medline TA:  Eur J Surg     Country:  NORWAY    
Other Details:
Languages:  eng     Pagination:  383-7     Citation Subset:  IM    
Department of Surgery, Latvian Medical Academy, Clinical Hospital Gailezers, Riga.
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MeSH Terms
Acute Disease
Enteral Nutrition* / adverse effects
Length of Stay
Middle Aged
Pancreatitis / mortality,  therapy*
Parenteral Nutrition
Postoperative Care
Prospective Studies
Survival Analysis

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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