| Ramipril and risk of hyperkalemia in chronic hemodialysis patients. | |
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MedLine Citation:
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PMID: 21755729 Owner: NLM Status: In-Process |
Abstract/OtherAbstract:
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Angiotensin converting enzyme (ACE) inhibitors provide well known cardiorenal-protective benefits added to antihypertensive effects in chronic renal disease. These agents are underused in management of patients receiving hemodialysis (HD) because of common concern of hyperkalemia. However, few studies have investigated effect of renin angiotensin aldosterone system (RAAS) blockade on serum potassium in hemodialysis patients. We assessed the safety of ramipril in patients on maintenance HD. We enrolled 28 adult end stage renal disease (ESRD) patients treated by maintenance HD and prescribed them ramipril in doses of 1.25 to 5 mg per day. They underwent serum potassium concentration measurements before ramipril introduction and in 1 to 3 months afterwards. No significant increase in kalemia was found. Results of our study encourage the use of ACE inhibitors in chronically hemodialyzed patients, but close potassium monitoring is mandatory. |
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Authors:
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Mirna Krajina-Andricević; Lada Zibar; Karin Juras; Sanda Goll-Barić; Jerko Barbić |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Collegium antropologicum Volume: 35 ISSN: 0350-6134 ISO Abbreviation: Coll Antropol Publication Date: 2011 Jun |
Date Detail:
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Created Date: 2011-07-15 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8003354 Medline TA: Coll Antropol Country: Croatia |
Other Details:
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Languages: eng Pagination: 537-42 Citation Subset: IM |
Affiliation:
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Vinkovci General Hospital, Department of Internal Medicine, Vinkovci, Croatia. mirna.k1@hotmail.com |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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