Document Detail


Raman-on-chip device and detection fibres with fibre Bragg grating for analysis of solutions and particles.
MedLine Citation:
PMID:  23344502     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
An all-fibre based Raman-on-chip setup is introduced which enables analysis of solutions and trapped particles without microscopes or objectives. Beside the novel quartz microfluidic chip, innovative multi-core single-mode fibres with integrated fibre Bragg gratings are used for detection. The limit of quantitation is 7.5 mM for urea and 2.5 mM for nicotine with linear Raman spectroscopy. This is an improvement of more than two orders of magnitude compared with previous fibre-based microfluidic Raman detection schemes. Furthermore, our device was combined with optical traps to collect Raman-on-chip spectra of spherical polymer beads.
Authors:
Sebastian Dochow; Martin Becker; Ron Spittel; Claudia Beleites; Sarmiza Stanca; Ines Latka; Kay Schuster; Jens Kobelke; Sonja Unger; Thomas Henkel; Günter Mayer; Jens Albert; Manfred Rothhardt; Christoph Krafft; Jürgen Popp
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2013-1-24
Journal Detail:
Title:  Lab on a chip     Volume:  -     ISSN:  1473-0189     ISO Abbreviation:  Lab Chip     Publication Date:  2013 Jan 
Date Detail:
Created Date:  2013-1-24     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101128948     Medline TA:  Lab Chip     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Affiliation:
Institute of Photonic Technology (IPHT), Albert Einstein Straße 9, 07745 Jena, Germany. juergen.popp@ipht-jena.de.
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