| Raised serum calcium in tuberculosis patients in Africa. | |
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MedLine Citation:
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PMID: 3443156 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Reports of raised serum calcium in the presence of tuberculosis have tended to be from centres where sunlight is plentiful. U.K.-based data have suggested that normocalcaemia prevails. In a prospective study of 15 African patients with pulmonary tuberculosis, resident in East Africa, corrected serum calcium was significantly lower in a control healthy group (2.59 mmol/l +/- 0.08 and 2.49 +/- 0.06 mmol/l respectively: P less than 0.001). Serum 25-hydroxy vitamin D was significantly lower in the patient group (median, 15.9 ng/ml, range 6.7-35.7) compared with the control group (median 26.2 ng/ml, range 10.5-45.9, P less than 0.05). No significant difference was found between patients and controls for 1,25-dihydroxy vitamin D or parathyroid hormone. No correlation was found between serum calcium and 1,25 (OH)2 D3. Serum albumin showed a negative correlation with radiographic extent of disease and with extent of cavitation. Where sunlight is plentiful, relatively high serum 25-hydroxy Vitamin D may give rise to raised serum calcium in the presence of tuberculosis. |
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Authors:
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P D Davies; H A Church; R C Brown; J S Woodhead |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: European journal of respiratory diseases Volume: 71 ISSN: 0106-4339 ISO Abbreviation: Eur J Respir Dis Publication Date: 1987 Nov |
Date Detail:
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Created Date: 1988-04-28 Completed Date: 1988-04-28 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 8006891 Medline TA: Eur J Respir Dis Country: DENMARK |
Other Details:
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Languages: eng Pagination: 341-4 Citation Subset: IM |
Affiliation:
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Department of Thoracic Medicine, Llandough Hospital, Penarth, South Glamorgan, U.K. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Calcium / blood Humans Hypercalcemia / etiology* Male Parathyroid Hormone / blood Serum Albumin / metabolism Tuberculosis, Pulmonary / blood* Vitamin D / blood |
| Chemical | |
Reg. No./Substance:
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0/Parathyroid Hormone; 0/Serum Albumin; 1406-16-2/Vitamin D; 7440-70-2/Calcium |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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