Document Detail

Radiotherapy during pregnancy: fact and fiction.
MedLine Citation:
PMID:  15863381     Owner:  NLM     Status:  MEDLINE    
Radiotherapy during pregnancy might cause harm to the developing fetus. Generally, pregnant women with malignant diseases are advised to delay radiotherapy until after delivery. However, this advice is not based on knowledge of the risks of radiation to the unborn child. In general, the expected radiation effects, such as mental retardation and organ malformations probably only arise above a threshold dose of 0.1-0.2 Gy. This threshold dose is not generally reached with curative radiotherapy during pregnancy, provided that tumours are located sufficiently far from the fetus and that precautions have been taken to protect the unborn child against leakage radiation and collimator scatter of the teletherapy machine; such precautions also reduce the risk of radiation-induced childhood cancer and leukaemia in the unborn child.
Henk B Kal; Henk Struikmans
Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  The Lancet. Oncology     Volume:  6     ISSN:  1470-2045     ISO Abbreviation:  Lancet Oncol.     Publication Date:  2005 May 
Date Detail:
Created Date:  2005-05-02     Completed Date:  2005-05-24     Revised Date:  2014-08-18    
Medline Journal Info:
Nlm Unique ID:  100957246     Medline TA:  Lancet Oncol     Country:  England    
Other Details:
Languages:  eng     Pagination:  328-33     Citation Subset:  IM    
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MeSH Terms
Abortion, Induced
Brain Neoplasms / radiotherapy
Breast Neoplasms / radiotherapy
Fetus / radiation effects
Hodgkin Disease / radiotherapy
Pregnancy Complications, Neoplastic / radiotherapy*
Radiation Dosage
Radiation Protection
Risk Factors
Uterine Cervical Neoplasms / radiotherapy

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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